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Codon-substitution models for detecting molecular adaptation at individual si...

Yang(Ziheng),Nielsen(Rasmus) Mol Biol Evol 2002-09-03

...BRCA1 genes from primates, and the phytochrome (PHY) gene family in angiosperms. Positive selection is detected in the l...

Identification of microcephalin, a protein implicated in determining the size...

Jackson(Andrew P),Eastwood(Helen),Bell(San... Am J Hum Genet 2002-07-26

...BRCA1 C-terminal domain-containing protein, is mutated in MCPH1 families sharing an ancestral 8p23 haplotype. This gene,...

Lumpectomy and breast radiotherapy in breast cancer patients with a family hi...

Leonard(Charles E),Sedlacek(Scot),Shapiro(... Breast J 2002-07-18

...BRCA1 or BRCA2 mutation. After a median follow-up of 3.9 years, 5 patients had local failure (2%), and 5 developed a con...

Pretest prediction of BRCA1 or BRCA2 mutation by risk counselors and the comp...

Euhus(David M),Smith(Kristin C),Robinson(L... J Natl Cancer Inst 2002-06-26

...BRCA1 and BRCA2 gene sequencing results unequivocally reported as negative or positive for a deleterious mutation. Sensi...

Interest in BRCA1/2 testing in a primary care population.

Armstrong(Katrina),Weber(Barbara),Ubel(Pet... Prev Med 2002-07-24

...BRCA1/2 testing and, when provided only limited information about BRCA1/2 testing, women at lowest risk of carrying a mu...

Structural and functional versatility of the FHA domain in DNA-damage signali...

Li(Jiejin),Williams(Brandi L),Haire(Lesley... Mol Cell 2002-07-03

...BRCA1 through either or both of two structurally distinct mechanisms. Although phospho-dependent binding is important fo...

Peritoneal lavage cytology: an assessment of its value during prophylactic oo...

Colgan(Terence J),Boerner(Scott L),Murphy(... Gynecol Oncol 2002-07-23

...BRCA1+, 18; BRCA2+, 10; BRCA-, 3). Intensive histopathologic examination was used in all 35 cases to identify occult car...

Cell proliferation and apoptosis in BRCA-associated hereditary ovarian cancer...

Levine(Douglas A),Federici(Mark G),Reuter(... Gynecol Oncol 2002-07-23

...BRCA1- and BRCA2-associated hereditary tumors, and apoptosis did not differ significantly between the hereditary and spo...

DNA repair/pro-apoptotic dual-role proteins in five major DNA repair pathways...

Bernstein(Carol),Bernstein(Harris),Payne(C... Mutat Res 2002-08-09

...BRCA1, ATM, ATR, WRN, BLM, Tip60 and p53); (2) NHEJ (the catalytic subunit of DNA-PK); (3) NER (XPB, XPD, p53 and p33(IN...

[Analysis of mutations in genes BRCA1 and BRCA2 among patients with breast an...

Duarte(F),Cameselle-Teijeiro(J F),Soares(R... Rev Clin Esp 2002-10-18

...BRCA1 and BRCA2 were identified; three of these mutations occurred in the gene BRCA1 and the other two in the gene BRCA2...

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