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TP53 BRCA1 CRISPR single-cell cancer

Lee(Soo-Chin),Bernhardt(Barbara A),Helzlso... Cancer 2002-04-09

Clinical testing for BRCA1/2 has been available since 1996. Interest in testing in the research and hypothetical situati...

De Leon Matsuda(Maria Lourdes),Liede(Alexa... Int J Cancer 2002-05-10

...BRCA1 mutations. We estimate the prevalence of BRCA mutations among unselected breast cancer cases in the Philippines to...

Montagna(Marco),Agata(Simona),De Nicolo(Ar... Int J Cancer 2002-04-18

Mutations in BRCA1 and BRCA2 genes confer a high risk of breast and ovarian cancer. As such, their identification is ess...

Thompson(Deborah),Easton(Douglas), Cancer Epidemiol Biomarkers... 2002-04-23

Previous studies have reported variation in BRCA1 breast and ovarian cancer risks with mutation position, suggesting tha...

Spurdle(Amanda B),Hopper(John L),Chen(Xiao... Cancer Epidemiol Biomarkers... 2002-04-23

...BRCA1 or BRCA2, and would explain approximately 3% of breast cancer. The BRCA2 N372H polymorphism appears to be associat...

Chen(Angus),Kleiman(Frida E),Manley(James ... J Biol Chem 2002-07-25

...BRCA1-(1-639) and BARD1 in bacteria can assemble a potent ubiquitin ligase activity. Purified BRCA1-(1-639)*BARD1 stimul...

Hedenfalk(Ingrid A),Ringnér(Markus),Trent(... Adv Cancer Res 2002-08-26

Large proportions of hereditary breast cancers are due to mutations in the two breast cancer susceptibility genes BRCA1 ...

Fries(Melissa H),Holt(Charlene),Carpenter(... Mil Med 2002-05-09

...BRCA1 and BRCA2 on a research basis to patients meeting specific diagnostic criteria, with risk for BRCA1 and BRCA2 muta...

Kim(Seong-Tae),Xu(Bo),Kastan(Michael B) Genes Dev 2002-04-01

...Brca1. These same sites in Smc1 are phosphorylated after treatment with UV irradiation or hydroxyurea in an Atm-independ...

Yazdi(Parvin T),Wang(Yi),Zhao(Song),Patel(... Genes Dev 2002-04-01

...BRCA1 and is phosphorylated in response to IR in an ATM- and NBS1-dependent manner. Using mass spectrometry, we establis...

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