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A second NAD(+)-dependent DNA ligase (LigB) in Escherichia coli.

Sriskanda(V),Shuman(S) Nucleic Acids Res 2002-04-19

...BRCA1 C-terminus domain (BRCT) and two of the four Zn-binding cysteines that are present in LigA and all other bacterial...

Clinical characteristics of individuals with germline mutations in BRCA1 and ...

Frank(Thomas S),Deffenbaugh(Amie M),Reid(J... J Clin Oncol 2002-04-17

...BRCA1 and BRCA2, 16 (21.6%) were nonfounder mutations, including seven in BRCA1 and nine in BRCA2. Twenty-one (28%) of 7...

Cancer incidence in a population of Jewish women at risk of ovarian cancer.

Liede(Alexander),Karlan(Beth Y),Baldwin(Ra... J Clin Oncol 2002-04-17

...BRCA1 gene. The overall cancer incidence among carriers of mutations in the BRCA1 gene was estimated to be 5,450 per 100...

An endonuclease/ligase based mutation scanning method especially suited for a...

Huang(Jianmin),Kirk(Brian),Favis(Reyna),So... Oncogene 2002-04-09

...BRCA1, and BRCA2 genes. The method has the sensitivity to detect K-ras mutations diluted 1 : 20 with wild-type DNA, a p5...

Acceleration of chromosomal instability of BRCA1-associated hereditary breast...

Miyoshi(Yasuo),Iwao(Kyoko),Ikeda(Noriko),E... Breast J 2002-04-25

Chromosomal instability (CIN) of BRCA1-associated hereditary breast cancers was studied by fluorescence in situ hybridiz...

Variation in BRCA1 cancer risks by mutation position.

Thompson(Deborah),Easton(Douglas), Cancer Epidemiol Biomarkers... 2002-04-23

Previous studies have reported variation in BRCA1 breast and ovarian cancer risks with mutation position, suggesting tha...

The BRCA2 372 HH genotype is associated with risk of breast cancer in Austral...

Spurdle(Amanda B),Hopper(John L),Chen(Xiao... Cancer Epidemiol Biomarkers... 2002-04-23

...BRCA1 or BRCA2, and would explain approximately 3% of breast cancer. The BRCA2 N372H polymorphism appears to be associat...

Autoubiquitination of the BRCA1*BARD1 RING ubiquitin ligase.

Chen(Angus),Kleiman(Frida E),Manley(James ... J Biol Chem 2002-07-25

...BRCA1-(1-639) and BARD1 in bacteria can assemble a potent ubiquitin ligase activity. Purified BRCA1-(1-639)*BARD1 stimul...

Deletion of tumor suppressor genes in Chinese non-small cell lung cancer.

An(Qian),Liu(Yong),Gao(Yanning),Huang(Jinf... Cancer Lett 2002-10-23

...BRCA1, DPC4 and DCC. Our data demonstrated frequent allelic losses of FHIT, p53, IFNA, VHL and p16 in both SCC and ADC. ...

A simple 'paper smear' method for dry collection, transport and storage of ce...

Kailash(U),Hedau(S),Gopalkrishna(V),Katiya... J Med Microbiol 2002-08-05

...BRCA1 and p53 genes were identical to those obtained from the same samples following collection in PBS, storage (-70 deg...

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