...BRCA1) and 13q12-13 (BRCA2) using polymerase chain reaction analysis of polymorphic microsatellite markers. These were c...
BRCA1 and BRCA2 mutations underlie a substantial proportion of all hereditary breast cancer. The mutational spectrum in ...
...BRCA1 mutations and one germline BRCA2 mutation, six of which were novel (Khoo et al., 2000). Knowledge of BRCA gene mut...
...BRCA1 (2289 U/ml), BRCA2 (2586 U/ml), and sporadic (3307 U/ml) cases (P = 0.5). For hereditary cases, optimal cytoreduct...
...BRCA1/2 mutation. The actual number of patients eligible to receive BRCA1/2 genetic testing outweighs the number of pati...
...BRCA1 and BRCA2 germline mutations. Needed however, among the physician community, medical geneticists, and genetic coun...
...BRCA1 and BRCA2, have established roles in genome integrity maintenance and in the control of homologous recombination. ...
...BRCA1 protein in the early induction of transcription of these two genes.
The proportions of mutation of BRCA1 and BRCA2 detected in familial breast cancer vary in different regions. Most breast...
...BRCA1. Aphidicolin, a DNA polymerase inhibitor, abolished both phase I DSBs and the activation of repair protein complex...
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