文献库搜索 | GeneLibs

Ghosh(A),Ran(X),Zhang(F),Gao(B),Xu(Y),Phoo... Nat Commun 2026-08-10

...BRCA1-deficient cancer cells, broader cancer dependencies on TRDMT1 remain unclear. Here, a TRDMT1 inhibitor (TRDMT1i) s...

Hasan(A),Demidova(EV),Priyadarshini(P),Czy... medRxiv 2026-08-31

...BRCA1 colocalization. SNP carrying cells impaired DNA repair causing genotoxic stress that is associated with increased ...

Duarte(SAC),Arantes(R),Martins(M),Moutinho... Clin Genet 2026-02-00

...BRCA1/2 variants accounting for 5.4%. The BRCA2 c.156_157insAlu variant was identified in 6 individuals (25% of all BRCA...

Abualsoud(BM),Alhomrani(M),Alamri(AS),Alsa... J Biomater Sci Polym Ed 2026-03-00

...BRCA1/2-mutated breast, ovarian, prostate, and pancreatic cancers. Despite their clinical success, challenges such as po...

Martin(D),Cheung(CC),Yang(C),Beauchamp(L),... Am J Surg Pathol 2026-09-15

...BRCA1, and BRCA2. Germline testing performed in 15 cases identified Lynch syndrome in 5 (33%). MMR immunohistochemistry ...

Jiménez-Guerrero(R),Belmonte-Fernández(A),... Mol Oncol 2026-02-00

...BRCA1 and CtIP, proteins involved in DNA damage repair by homologous recombination. We showed that SCF(β-TrCP) plays a k...

Ouhajjou(A),Mazouji(O),Nejjari(C),Incitti(... Front Cell Dev Biol 2026-00-00

...BRCA1/2-mutated cancers and later in other HR-deficient tumors. PARP inhibitors have become essential components of firs...

Qian(J),Tanaka(K),Yasui(A),Ui(A) Commun Biol 2026-09-15

...BRCA1 and RAD51 to the DSB site. CHRAC promotes later RAD51-mediated HR steps through additional nucleosome-remodeling a...

Zhu(Y),Wang(Y),Shen(Z),Shen(L),Liu(H),Xian... Chin Med J (Engl) 2026-06-20

...BRCA1/2 mutations (g BRCA1/2 m) in ovarian cancer is controversial, and the clinical implications of specific mutation d...

Quaas(M),Kohler(R),Nöltner(L),Schmidbauer(... Cell Death Differ 2026-01-00

BRCA1 and BRCA2 proteins are crucial for DNA repair through homologous recombination (HR), which predominantly takes pla...