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Comparison of DNA- and RNA-based methods for detection of truncating BRCA1 mu...

Andrulis(Irene L),Anton-Culver(Hoda),Beck(... Hum Mutat 2002-08-05

A number of methods are used for mutational analysis of BRCA1, a large multi-exon gene. A comparison was made of five me...

Familial ovarian cancer.

Volm(Tanja) Curr Womens Health Rep 2002-07-26

...BRCA1 or BRCA2 genes are at increased risk for the development not only of breast, but of ovarian cancer. The estimated ...

Gene therapy of ovarian cancer.

Bauknecht(Thomas),Meinhold-Heerlein(Ivo) Curr Womens Health Rep 2002-07-26

...BRCA1, Her2/neu, Bcl-2, MDR, EIA, and HSV-TK genes) have been performed to test the relative safety of different strateg...

Screening behaviors among African American women at high risk for breast canc...

Kinney(Anita Yeomans),Emery(Gwyn),Dudley(W... Oncol Nurs Forum 2002-07-02

...BRCA1 mutation; no subjects had breast cancer.,Survey through in-person or telephone interviews.,Belief in God as a cont...

A CHEK2 genetic variant contributing to a substantial fraction of familial br...

Vahteristo(Pia),Bartkova(Jirina),Eerola(Ha... Am J Hum Genet 2002-08-20

CHEK2 (previously known as "CHK2") is a cell-cycle-checkpoint kinase that phosphorylates p53 and BRCA1 in response to DN...

Crystal structure of human 53BP1 BRCT domains bound to p53 tumour suppressor.

Derbyshire(Dean J),Basu(Balaku P),Serpell(... EMBO J 2002-09-05

The BRCT (BRCA1 C-terminus) is an evolutionary conserved protein-protein interacting module found as single, tandem or m...

Checking in on Cds1 (Chk2): A checkpoint kinase and tumor suppressor.

McGowan(Clare H) Bioessays 2002-08-12

...Brca1. A role for Cds1 in repair is suggested by the finding that it interacts with the Holliday junction resolving acti...

Changes in BRCA1 and BRCA2 expression produced by chemotherapeutic agents in ...

Su(Jiangfeng),Ciftci(Kadriye) Int J Biochem Cell Biol 2002-08-30

...BRCA1 and BRCA2), and the association of cell cycle progression in human breast cancer and normal breast epithelial cell...

Failure of BRCA1 dysfunction to alter ovarian cancer survival.

Buller(Richard E),Shahin(Mark S),Geisler(J... Clin Cancer Res 2002-10-17

...BRCA1-related ovarian cancer. None have controlled for other mechanisms of BRCA1 silencing in the control cohort.,Fifty-...

Attenuation of the formation of DNA-repair foci containing RAD51 in Fanconi a...

Digweed(Martin),Rothe(Susanne),Demuth(Ilja... Carcinogenesis 2002-08-30

...BRCA1 for visualisation. IR induced foci detected with anti-RAD51, but not those detected with anti-MRE11, are reduced i...

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