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Interpreting epidemiological research: blinded comparison of methods used to ...

Eng(C),Brody(L C),Wagner(T M),Devilee(P),V... J Med Genet 2002-03-07

...BRCA1, most published estimates of the prevalence of mutations in this gene have been derived from studies that have use...

BRCA2 gene mutations in Greek patients with familial breast cancer.

Armakolas(Athanasios),Ladopoulou(Angela),K... Hum Mutat 2002-02-12

...BRCA1 and BRCA2 genes, the two major predisposing genes in familial and to early onset breast and ovarian cancer, has re...

Cost-effectiveness of raloxifene and hormone replacement therapy in postmenop...

Armstrong(K),Chen(T M),Albert(D),Randall(T... Obstet Gynecol 2002-01-14

...BRCA1/2 mutation). These results can help inform decisions about postmenopausal therapy until the results of large scale...

A DNA damage-regulated BRCT-containing protein, TopBP1, is required for cell ...

Yamane(Kazuhiko),Wu(Xianglin),Chen(Junjie) Mol Cell Biol 2002-01-29

BRCA1 carboxyl-terminal (BRCT) motifs are present in a number of proteins involved in DNA repair and/or DNA damage-signa...

Gene-expression profiles in hereditary breast cancer.

Chinnaiyan(Arul M),Rubin(Mark A) Adv Anat Pathol 2002-02-21

...BRCA1 and BRCA2, both of which increase the lifetime risk of developing breast cancer. The genome-wide perspective ident...

The Chinese hamster FANCG/XRCC9 mutant NM3 fails to express the monoubiquitin...

Wilson(J B),Johnson(M A),Stuckert(A P),Tru... Carcinogenesis 2002-02-04

...BRCA1 in DNA damage induced foci. In this study, we have assigned NM3, a nitrogen mustard-hypersensitive Chinese hamster...

Clinical management of women with genomic BRCA1 and BRCA2 mutations.

Chang(J),Elledge(R M) Breast Cancer Res Treat 2002-04-02

There is increasing evidence that BRCA1 and BRCA2 associated tumors may differ from sporadic cancers. The purpose of thi...

DNA methylation patterns in hereditary human cancers mimic sporadic tumorigen...

Esteller(M),Fraga(M F),Guo(M),Garcia-Fonci... Hum Mol Genet 2002-03-27

...BRCA1, APC, LKB1, CDH1, p16(INK4a), p14(ARF), MGMT, GSTP1 and RARbeta2) and 5-methylcytosine DNA content, in inherited (...

The LIM domain protein LMO4 interacts with the cofactor CtIP and the tumor su...

Sum(Eleanor Y M),Peng(Benjamin),Yu(Xin),Ch... J Biol Chem 2002-04-15

...BRCA1 and CtIP had no effect on the association of BRCA1 with LMO4. A stable complex comprising LMO4, BRCA1, and CtIP wa...

Novel germline BRCA1 and BRCA2 mutations in breast and breast/ovarian cancer ...

Machackova(E),Damborsky(J),Valik(D),Foreto... Hum Mutat 2002-03-07

...BRCA1 and BRCA2 genes. In BRCA1, two novel frame shift mutations were identified as 3761-3762delGA and 2616-2617ins10; i...

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