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TP53 BRCA1 CRISPR single-cell cancer

Yamane(K),Katayama(E),Tsuruo(T) Biochem Biophys Res Commun 2001-02-02

The BRCT regions are two repeating structures in BRCA1 at the carboxyl-terminus and are ubiquitous in some proteins invo...

Chappuis(P O),Kapusta(L),Bégin(L R),Wong(N... J Clin Oncol 2001-01-25

...BRCA1/2 mutations is less clear, and the relationship between BRCA1/2 mutation status, p27(Kip1) protein levels, and out...

Stoppa-Lyonnet(D),Ansquer(Y),Dreyfus(H),Ga... J Clin Oncol 2001-01-25

...BRCA1 patients and 91 non-BRCA1 patients). The differences between the BRCA1 and non-BRCA1 groups regarding overall surv...

Tibbetts(R S),Cortez(D),Brumbaugh(K M),Scu... Genes Dev 2001-01-18

...BRCA1 gene encodes a tumor suppressor that is mutated in 50% of familial breast cancers. The BRCA1 protein has been impl...

Thomas(D C) Genet Epidemiol 2001-02-01

...BRCA1 and BRCA2, and their characterization is reviewed. Interactions of major susceptibility genes, metabolic genes, an...

Esteller(M) Eur J Cancer 2001-10-11

...BRCA1 may lead to four specific genetic lesions, microsatellite instability, G to A transitions, steroid-related adducts...

Gershoni-Baruch(R),Dagan(E),Israeli(D),Kas... Eur J Cancer 2001-10-11

...BRCA1/2 mutation carriers, genotyped for the three predominant Jewish founder BRCA1/2 mutations (185delAG, 5382insC and ...

Kuperwasser(C),Hurlbut(G D),Kittrell(F S),... Am J Pathol 2001-01-04

...BRCA1. Although mammary tumors were rarely detected in BALB/c-p53(-/-) female mice, when glands from BALB/c-p53(-/-) mic...

Grzybowska(E),Zientek(H),Jasinska(A),Rusin... Hum Mutat 2001-01-11

Germ-line mutations in BRCA1 and BRCA2 genes result in a significantly increased risk of breast and ovarian cancer. Othe...

Shiri-Sverdlov(R),Oefner(P),Green(L),Baruc... Hum Mutat 2001-01-11

In Ashkenazi (East European) Jews, three predominant mutations in BRCA1 (185delAG and 5382insC) and BRCA2 (6174delT) acc...

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