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TP53 BRCA1 CRISPR single-cell cancer

Kiechle(M),Gross(E),Schwarz-Boeger(U),Pfis... Hum Mutat 2001-01-11

Germline mutations in the BRCA1 and BRCA2 gene account for the majority of high-risk breast/ovarian cancer families. We ...

Houshmand(S L),Campbell(C T),Briggs(S E),M... Oncol Nurs Forum 2001-05-31

...BRCA1- and BRCA2-positive women.,Published research articles, professional review articles, textbooks.,Women with BRCA1 ...

Shih(H A),Nathanson(K L),Seal(S),Collins(N... Clin Cancer Res 2001-05-31

...BRCA1 or BRCA2 (P < 0.001). BRCA1 and BRCA2 mutations were twice as common in the presence of a reported second nonovari...

Tait(D L),Obermiller(P S),Holt(J T) Gynecol Oncol 2001-01-04

...BRCA1 vector, MFG-BRCA1, for ovarian cancer gene therapy.,MFG-BRCA1 was packaged in human 293 renal cells and manufactur...

Goshen(R),Chu(W),Elit(L),Pal(T),Hakimi(J),... Gynecol Oncol 2001-01-04

...BRCA1 carriers, which also includes ovarian carcinoma, fallopian tube carcinoma, and primary peritoneal carcinoma.,Fifty...

Gronau(K A),Semple(J L) Ann Plast Surg 2001-03-15

...BRCA1 or BRCA2 may be offered prophylactic mastectomies. The authors present an overview of risk factors so that surgeon...

Kanai(M),Uchida(M),Hanai(S),Uematsu(N),Uch... Biochem Biophys Res Commun 2001-01-04

...BRCA1 were recently found to localize to the centrosome at mitosis. We found that PARP is localized to the centrosomes a...

Paull(T T),Rogakou(E P),Yamazaki(V),Kirchg... Curr Biol 2001-02-01

...BRCA1 also colocalized with gamma-H2AX and was recruited to these sites before Rad50 or Rad51. Exposure of cells to the ...

Rodríguez(J A),Henderson(B R) J Biol Chem 2001-01-18

...Brca1 confer increased susceptibility to breast and ovarian cancers. BRCA1 is a 1863-amino acid protein with roles in tr...

Brown(P H),Lippman(S M) Breast Cancer Res Treat 2001-01-25

...BRCA1 mutation carriers); raloxifene in breast cancer prevention; other SERMs; SERM resistance; and new agents and combi...

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