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TP53 BRCA1 CRISPR single-cell cancer

Goodwin(P J) Breast Cancer Res Treat 2001-01-25

...BRCA1 and BRCA2 has made it possible to identify mutation carriers within some of these families. Management of breast c...

Tauchi(H),Kobayashi(J),Morishima(K),Matsuu... J Biol Chem 2001-02-08

...BRCA1 C terminus domain. The protein interacts with hMRE11 to form a complex with a nuclease activity for initiation of ...

Gilpin(C A),Carson(N),Hunter(A G) Clin Genet 2001-03-01

The medical community and general population have become aware that genetic testing is available to look for BRCA1 and B...

Kinoshita(Y),Jarell(A D),Flaman(J M),Foltz... J Biol Chem 2001-04-05

...BRCA1 C-terminal domain, clusters of acidic amino acids and consensus motifs for post-translational modification by SUMO...

Cappelli(E),Rossi(O),Chessa(L),Frosina(G) Eur J Biochem 2001-02-01

...BRCA1 gene product suggest that a DNA-repair defect may underlie, at least in part, the radiation sensitivity in A-T cel...

Annab(L A),Hawkins(R E),Solomon(G),Barrett... Breast Cancer Res 2001-07-05

...BRCA1 antisense retroviral constructs into BG-1 estrogen-dependent ovarian adenocarcinoma cells resulted in reduced BRCA...

Ottini(L),D'Amico(C),Noviello(C),Lauro(S),... Breast Cancer Res 2001-07-19

...BRCA1 and BRCA2 genes in 136 unrelated Italian breast/ovarian cancer patients. In the sample tested, BRCA1 and BRCA2 equ...

Hu(Y F),Miyake(T),Ye(Q),Li(R) J Biol Chem 2001-01-26

...BRCA1, account for a significant proportion of hereditary breast and ovarian cancers. The BRCA1 C-terminal (BRCT) domain...

Wu(X),Webster(S R),Chen(J) J Biol Chem 2001-06-21

...BRCA1, and ATM are frequently mutated in human cancer. Checkpoint kinase 2 (Chk2) is a DNA damage-activated protein kina...

Sarantaus(L),Huusko(P),Eerola(H),Launonen(... Eur J Hum Genet 2001-02-01

...BRCA1 gene, and earlier age of ovarian cancer onset in families with BRCA1 mutations compared with families with BRCA2 m...

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