The BRCT regions are two repeating structures at BRCA1 carboxyl-terminus and are ubiquitous in some proteins involved in...
...BRCA1, involved in breast and ovarian cancers. Finally, the gene encoding SNF5/Ini1, a subunit common to all mammalian S...
...BRCA1 mRNA levels (0.519 +/- 0.570 (BRCA1 / beta-glucuronidase mRNA ratios)), and a weak but significant (r = 0.390, P <...
...BRCA1 mutation carriers, thus suggesting a different role of the AR-CAG polymorphism in sporadic and inherited breast ca...
...BRCA1 C-terminal) domain protein that physically interacts with Smad2 via its BRCT domains. We examine the activity of S...
...Brca1 protein. Our results demonstrate that full-length murine Brca1 is identical to human BRCA1 with respect to its cel...
...BRCA1 or BRCA2 germ-line mutations than in sporadic breast cancers (odds ratio, 2.8; P = 0.0003). Then, we compared the ...
...Brca1 locus a modification (Brca1(tr)) that eliminates the C-terminal half of the protein product and obtained results i...
Mutation analysis for autosomal dominant hereditary breast/ovarian cancer genes (BRCA1/BRCA2) became an important techni...
...BRCA1 or BRCA2 mutations.
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