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Breast cancer after mantle irradiation for Hodgkin's disease: correlation of ...

Gaffney(D K),Hemmersmeier(J),Holden(J),Mar... Int J Radiat Oncol Biol Phy... 2001-03-15

...BRCA1 or BRCA2. In the Hodgkin's disease group, LOH was observed in 30% of tumors at BRCA1 and 10% of tumors at BRCA2 vs...

Allelic imbalance on chromosomes 13 and 17 and mutation analysis of BRCA1 and...

Försti(A),Luo(L),Vorechovsky(I),Söderberg(... Carcinogenesis 2001-03-15

...BRCA1 marker) the proportion of twin pairs with the same LOH was significantly higher than expected. These regions may r...

Mutagen sensitivity of human lymphoblastoid cells with a BRCA1 mutation in co...

Speit(G),Trenz(K),Schütz(P),Bendix(R),Dörk(T) Cytogenet Cell Genet 2001-03-29

...BRCA1 cells, thus indicating a difference in the pathways leading to mutagen sensitivity in cells with a BRCA1 or an AT ...

Transactivation of the p21 promoter by BRCA1 splice variants in mammary epith...

Lu(M),Arrick(B A) Oncogene 2001-03-22

...BRCA1 (BRCA1L) as well as by two splice variants that lack most of exon 11 (BRCA1S and BRCA1S-9,10). In contrast, two ce...

Evaluation of radioinduced damage and repair capacity in blood lymphocytes of...

Nascimento(P A),da Silva(M A),Oliveira(E M... Braz J Med Biol Res 2001-05-17

...BRCA1 and BRCA2 genes are discussed. Both parameters adopted proved to be sensitive and reproducible: the dose-response ...

Human BRCA1 gene rescues the embryonic lethality of Brca1 mutant mice.

Chandler(J),Hohenstein(P),Swing(D A),Tessa... Genesis 2001-05-03

...BRCA1 gene into the germline of Brca1 knockout mice. Surprisingly, we have found that the embryonic lethality of Brca1 k...

A common deletion at chromosomal region 17q21 in sporadic prostate tumors dis...

Dai(Q),Deubler(D A),Maxwell(T M),Zhu(X L),... Genomics 2001-07-12

...BRCA1) on chromosome 17. This suggested that genes at 17q21 may play a pivotal role in prostate cancer progression, and ...

A novel host cell reactivation assay to assess homologous recombination capac...

Slebos(R J),Taylor(J A) Biochem Biophys Res Commun 2001-04-05

...BRCA1 and -2 are involved in the proper control of homologous recombination, suggesting a role of this type of repair in...

Prevalence and penetrance of germline BRCA1 and BRCA2 mutations in a populati...

Risch(H A),McLaughlin(J R),Cole(D E),Rosen... Am J Hum Genet 2001-04-05

...BRCA1, with denaturing gradient gel electrophoresis for the remainder of BRCA1, and with PTT for exons 10 and 11 of BRCA...

Expression profiles and intergenic structure of head-to-head oriented Brca1 a...

Dimitrov(S),Brennerova(M),Forejt(J) Gene 2001-07-05

...Brca1/BRCA1 and Nbr1/NBR2 genes lie head-to-head, being transcribed from the opposite strands. The normal function of Br...

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