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TP53 BRCA1 CRISPR single-cell cancer

Pals(G),Young(C),Mao(H S),Worsham(M J) J Biochem Biophys Methods 2001-05-21

...BRCA1 gene containing a single base substitution and deletion, respectively. Polymerase chain reactions of small fragmen...

Gao(B),Shen(X),Kunos(G),Meng(Q),Goldberg(I... FEBS Lett 2001-03-29

...BRCA1) confer a high risk for breast and ovarian cancer in women and prostate cancer in men. The BRCA1 protein contribut...

Orban(T I),Olah(E) Biochem Biophys Res Commun 2001-03-22

...BRCA1 mRNA pool and the expression profile of four predominant BRCA1 splice variants in asynchronous and in G1/S synchro...

Moore(D F),Chatterjee(N),Pee(D),Gail(M H) Genet Epidemiol 2001-04-05

...BRCA1 or BRCA2 was 0.56, a figure that was lower than previously estimated from highly affected families. The method tha...

Julian-Reynier(C),Sobol(H),Sévilla(C),Nogu... Psychooncology 2001-03-01

Due to the technical difficulties involved in identifying BRCA1/2 genetic mutations, the affected patients have to be in...

Brekelmans(C T),Seynaeve(C),Bartels(C C),T... J Clin Oncol 2001-04-12

...BRCA1/2 mutation carriers is unknown. We present first results from a single large family cancer clinic.,Women with brea...

Karabinis(M E),Larson(D),Barlow(C),Wynshaw... Carcinogenesis 2001-04-05

...Brca1 or ATM are not highly susceptible to breast cancer. We proposed that heterozygosity for a mutant allele of Brca1 o...

Pääkkönen(K),Sauramo(S),Sarantaus(L),Vahte... Genet Epidemiol 2001-04-05

...BRCA1 and BRCA2 genomic regions. Our haplotype association study did not reveal any founder effects for either BRCA1 or ...

Vallon-Christersson(J),Cayanan(C),Haraldss... Hum Mol Genet 2001-06-07

...BRCA1 and further support the role of BRCA1 missense mutations in disease predisposition. We also report a discrepancy b...

van der Luijt (R B),van Zon (P H),Jansen(R... J Med Genet 2001-05-31

Germline mutations in either of the two major breast cancer predisposition genes, BRCA1 and BRCA2, account for a signifi...

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