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Current perspectives on BRCA1- and BRCA2-associated breast cancers.

Phillips(K A) Intern Med J 2001-12-20

...BRCA1- and BRCA2-associated hereditary breast cancers are reviewed. Research into BRCA1- and BRCA2-associated breast can...

Brca1 required for T cell lineage development but not TCR loci rearrangement.

Mak(T W),Hakem(A),McPherson(J P),Shehabeld... Nat Immunol 2001-04-19

Brca1 (breast cancerl, early onset) deficiency results in early embryonic lethality. As Brca1 is highly expressed in the...

Psychological adjustment to familial genetic risk assessment: differences in ...

Ritvo(P),Robinson(G),Irvine(J),Brown(L),Ma... Patient Educ Couns 2001-05-03

...BRCA1/BRCA2 mutations) or their absence. In this paper we report on the psychological responses of women given familial-...

Germline mutations in BRCA1 and BRCA2 in breast-ovarian families from a breas...

Martin(A M),Blackwood(M A),Antin-Ozerkis(D... J Clin Oncol 2001-05-17

...BRCA1 or BRCA2 may be as high as 98% depending on the characteristics of the families, suggesting that mutations in BRCA...

Breast cancer: hormones and other risk factors.

Hulka(B S),Moorman(P G) Maturitas 2001-06-14

...BRCA1 and BRCA2 genes are important correlates of lifetime risk. Genetic polymorphisms associated with estrogen synthesi...

International collaboration provides convincing linkage replication in comple...

Cavanaugh(J), Am J Hum Genet 2001-06-07

...BRCA1 and BRCA2, most attempts have failed to produce replicable linkage findings. For example, in multiple sclerosis an...

Ataxia telangiectasia mutated (ATM) kinase and ATM and Rad3 related kinase me...

Gatei(M),Zhou(B B),Hobson(K),Scott(S),Youn... J Biol Chem 2001-07-05

...Brca1 phosphorylation in vivo after the exposure of cells to UV light. Moreover, ATR associates with Brca1; ATR and Brca...

Genetic testing for breast cancer: where are health care providers in the dec...

Velicer(C M),Taplin(S) Genet Med 2001-08-09

...BRCA1/2 knowledge, genetic testing intentions, and communication patterns in breast cancer survivors (survivors).,A popu...

c-Fos oncogene regulator Elk-1 interacts with BRCA1 splice variants BRCA1a/1b...

Chai(Y),Chipitsyna(G),Cui(J),Liao(B),Liu(S... Oncogene 2001-05-10

...BRCA1 splice variants BRCA1a and BRCA1b using GST-pull down assays, co-imunoprecipitations/Western blot analysis of cell...

Identification of a novel transcriptional repressor element located in the fi...

Suen(T C),Goss(P E) Oncogene 2001-05-10

...BRCA1 in non-familial breast cancer has been shown in several recent studies. Understanding how BRCA1 expression is regu...

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