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TP53 BRCA1 CRISPR single-cell cancer

Plon(S E),Peterson(L E),Friedman(L C),Rich... Genet Med 2001-11-01

To define the impact of a negative BRCA1 test result on subsequent breast cancer screening behavior in women.,Longitudin...

Campbell(M),Aprelikova(O N),van der Meer(R... Cancer Gene Ther 2001-11-01

...BRCA1 (AdBRCA1), murine Brca1 (AdBrca1), three clinically relevant human mutant BRCA1 proteins (t340, C61G, and 1853Stop...

Ruiz-Flores(P),Calderón-Garcidueñas(A L),B... Rev Invest Clin 2001-06-28

...BRCA1 and BRCA2 genes are frequently mutated. These genes are the two main BC susceptibility genes. BRCA1 predispose to ...

Aunoble(B),Bernard-Gallon(D),Bignon(Y J) Oncol Rep 2001-07-05

...BRCA1 and BRCA2 expression, in response to cytotoxic agents, may be dependent on p53 status. To investigate this possibi...

Ruffner(H),Joazeiro(C A),Hemmati(D),Hunter... Proc Natl Acad Sci U S A 2001-05-21

...BRCA1-null human breast cancer cells, HCC1937. Additionally, these mutations within the BRCA1 RING domain are not capabl...

Bajdik(C D),Raboud(J M),Schechter(M T),McG... Math Biosci 2001-07-05

The BRCA1 gene and its relationship to family history of breast/ovarian cancer are difficult to study in a population be...

Esteller(M),Corn(P G),Baylin(S B),Herman(J G) Cancer Res 2001-05-10

...BRCA1, hMLH1, GSTP1, MGMT, CDH1, TIMP3, and DAPK), each rigorously characterized for association with abnormal gene sile...

Buller(R E),Lallas(T A),Shahin(M S),Sood(A... Clin Cancer Res 2001-06-14

...BRCA1-related hereditary breast cancers suggest that both unique and specific BRCA1-associated p53 mutations may be foun...

Greenblatt(M S),Chappuis(P O),Bond(J P),Ha... Cancer Res 2001-06-14

...BRCA1 or BRCA2 germ-line mutations than in sporadic breast cancers (odds ratio, 2.8; P = 0.0003). Then, we compared the ...

Ludwig(T),Fisher(P),Ganesan(S),Efstratiadi... Genes Dev 2001-07-05

...Brca1 locus a modification (Brca1(tr)) that eliminates the C-terminal half of the protein product and obtained results i...

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