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The usefulness of antibodies to the BRCA1 protein in detecting the mutated BR...

Pérez-Vallés(A),Martorell-Cebollada(M),Nog... J Clin Pathol 2001-06-21

...BRCA1 associated and non-BRCA1 associated breast tumours.,Four commercially available anti-BRCA1 antibodies were used on...

Double-strand-break-induced homologous recombination in mammalian cells.

Johnson(R D),Jasin(M) Biochem Soc Trans 2001-09-06

...BRCA1. This paper summarizes results from a number of recent studies.

Swift is a novel BRCT domain coactivator of Smad2 in transforming growth fact...

Shimizu(K),Bourillot(P Y),Nielsen(S J),Zor... Mol Cell Biol 2001-06-28

...BRCA1 C-terminal) domain protein that physically interacts with Smad2 via its BRCT domains. We examine the activity of S...

Impaired DNA damage response in cells expressing an exon 11-deleted murine Br...

Huber(L J),Yang(T W),Sarkisian(C J),Master... Mol Cell Biol 2001-06-28

...Brca1 protein. Our results demonstrate that full-length murine Brca1 is identical to human BRCA1 with respect to its cel...

Nine novel conserved motifs in BRCA1 identified by the chicken orthologue.

Orelli(B J),Logsdon Jr(J M),Bishop(D K) Oncogene 2001-08-09

...BRCA1 gene from chicken; the gene encodes a 1749 amino acid protein that is 33% identical to human BRCA1. Phylogenetic a...

The frequency of founder mutations in the BRCA1, BRCA2, and APC genes in Aust...

Bahar(A Y),Taylor(P J),Andrews(L),Proos(A)... Cancer 2001-08-09

...BRCA1 185delAG, BRCA1 5382insC, BRCA2 6174delT, and APC I1307K at frequencies of 1.0--1.1%, 0.2--0.3%, 0.6--1.4%, and 6....

Effect of omega-3 fatty acid (docosahexanoic acid) on BRCA1 gene expression a...

Kachhap(S K),Dange(P P),Santani(R H),Sawan... Cancer Biother Radiopharm 2001-12-18

...BRCA1 mRNA expression was observed. Further, when DHA was administered to cells along with LA + E2, no change in BRCA1 e...

Mutation analysis of the CHK2 gene in families with hereditary breast cancer.

Allinen(M),Huusko(P),Mäntyniemi(S),Launone... Br J Cancer 2001-08-23

...BRCA1, the product of one of the 2 known major susceptibility genes to hereditary breast cancer, it also more directly m...

Psychological issues among children of hereditary breast cancer gene (BRCA1/2...

Tercyak(K P),Peshkin(B N),Streisand(R),Ler... Psychooncology 2001-08-30

...BRCA1/2 susceptibility genes. As part of a longitudinal investigation of the outcomes of BRCA1/2 testing in adults, 20 c...

Detection of germline mutations in the BRCA1 gene by RNA-based sequencing.

Jakubowska(A),Górski(B),Byrski(T),Huzarski... Hum Mutat 2001-12-04

BRCA1 mutation detection is expensive and has sensitivity limitations, which might at least partially be overcome by RNA...

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