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TP53 BRCA1 CRISPR single-cell cancer

Xia(F),Taghian(D G),DeFrank(J S),Zeng(Z C)... Proc Natl Acad Sci U S A 2001-08-30

...BRCA1, which is involved in multiple DNA repair pathways, BRCA2 status had no impact on the other principal double-stran...

Kozlowski(P),Krzyzosiak(W J) Nucleic Acids Res 2001-09-06

...BRCA1 and BRCA2, are scanned for scattered unknown mutations and/or when a large number of DNA samples is screened for s...

García-Closas(M),Egan(K M),Abruzzo(J),Newc... Cancer Epidemiol Biomarkers... 2001-07-12

...BRCA1/2 genes in a subset of phenol-chloroform DNA extracts. Relative to DNA extracted by phenol-chloroform from cytobru...

Kachhap(S K),Vetale(S P),Dange(P),Ghosh(S ... Cell Biol Int 2001-08-02

...BRCA1 expression was lower in MCF-7 cells than in HeLa cells. Since BRCA1 is known to play a role in the maintenance of ...

Chen(G C),Guan(L S),Yu(J H),Li(G C),Choi K... Biochem Biophys Res Commun 2001-07-12

...BRCA1 (the BRCT domain), a domain involved in the t transactivation activity of BRCA1. Coimmunoprecipitation assays demo...

Mäkiniemi(M),Hillukkala(T),Tuusa(J),Reini(... J Biol Chem 2001-09-06

...Brca1 to foci that do not represent sites of ongoing DNA replication. Inhibition of DNA synthesis leads to relocalizatio...

Leasure(C S),Chandler(J),Gilbert(D J),Hous... Gene 2001-08-16

...BRCA1 and BRCA2 has provided an insight into the mechanism of how these molecules function as tumor suppressors. Several...

Ricevuto(E),Sobol(H),Stoppa-Lyonnet(D),Gul... Clin Cancer Res 2001-09-20

The aim of this study was to develop a protocol for reliable, sensitive, and cost-effective mutation scanning of the BRC...

Chang(J),Hilsenbeck(S G),Sng(J H),Wong(J),... Clin Cancer Res 2001-09-20

...BRCA1. Only 5.6% (2 of 36) of BRCA1-associated breast cancers did not have this morphological profile, compared with 94....

Moynahan(M E),Cui(T Y),Jasin(M) Cancer Res 2001-07-12

...Brca1- and BRCA2-deficient cells are defective in homology-directed chromosomal break repair. We confirm that Brca1-defi...

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