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Germ line mutations associated with breast cancer susceptibility.

Iau(P T),Macmillan(R D),Blamey(R W) Eur J Cancer 2001-03-29

...BRCA1 mutations are more commonly associated with ovarian cancer than BRCA2 mutations. BRCA1 cancers tend to have more d...

Role of direct interaction in BRCA1 inhibition of estrogen receptor activity.

Fan(S),Ma(Y X),Wang(C),Yuan(R Q),Meng(Q),W... Oncogene 2001-03-29

...BRCA1 and in a breast cancer cell line that lacks endogenous functional BRCA1 (HCC1937). In addition, BRCA1 blocked the ...

[Analysis of mutations in the BRCA1 gene in patients with cancer of the breas...

Soares(R),Amendoeira(I),Monteiro(P),Lopes(... Acta Med Port 2001-03-22

Germline mutations in the BRCA1 gene confer an increased susceptibility to breast and ovarian cancer. Approximately 460 ...

DNA double-strand breaks: signaling, repair and the cancer connection.

Khanna(K K),Jackson(S P) Nat Genet 2001-04-12

...Brca1 and Brca2 have been linked to such pathways, and how accumulating evidence is connecting deficiencies in cellular ...

Germline BRCA1 mutations in Iranian women with breast cancer.

Ghaderi(A),Talei(A),Farjadian(S),Mosalaei(... Cancer Lett 2001-04-26

BRCA1 is known as a familial early onset breast cancer gene located in the long arm of chromosome 17. Alterations in thi...

A single nucleotide polymorphism in the RAD51 gene modifies cancer risk in BR...

Levy-Lahad(E),Lahad(A),Eisenberg(S),Dagan(... Proc Natl Acad Sci U S A 2001-12-04

BRCA1 and BRCA2 carriers are at increased risk for both breast and ovarian cancer, but estimates of lifetime risk vary w...

A probability model for predicting BRCA1 and BRCA2 mutations in breast and br...

Vahteristo(P),Eerola(H),Tamminen(A),Blomqv... Br J Cancer 2001-04-19

Germline mutations in BRCA1 and BRCA2 genes predispose to hereditary breast and ovarian cancer. Our aim was to find asso...

The retinoblastoma gene: a prototypic and multifunctional tumor suppressor.

Zheng(L),Lee(W H) Exp Cell Res 2001-04-12

...BRCA1/2.

Primary ovarian carcinomas display multiple methylator phenotypes involving k...

Strathdee(G),Appleton(K),Illand(M),Millan(... Am J Pathol 2001-04-05

...BRCA1, HIC1, MINT25, MINT31, MLH1, p73 and hTR) were found to be methylated in a significant proportion of the ovarian t...

Influence of chemically modified tetracyclines on proliferation, invasion and...

Meng(Q),Xu(J),Goldberg(I D),Rosen(E M),Gre... Clin Exp Metastasis 2001-03-29

...BRCA1. In addition, CMT-3 and CMT-8 abolished or reduced spontaneous and HGF/SF-induced cell invasion and migration in U...

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