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TP53 BRCA1 CRISPR single-cell cancer

Russo(A),Zanna(I),Tubiolo(C),Migliavacca(M... Anticancer Res 2001-02-22

...BRCA1). The first step in identifying individuals at high risk of developing a specific inherited form of cancer, and wh...

Hedenfalk(I),Duggan(D),Chen(Y),Radmacher(M... N Engl J Med 2001-02-22

Many cases of hereditary breast cancer are due to mutations in either the BRCA1 or the BRCA2 gene. The histopathological...

Cantor(S B),Bell(D W),Ganesan(S),Kass(E M)... Cell 2001-05-17

...BRCA1 binding function. Thus, BACH1/BRCA1 complex formation contributes to a key BRCA1 activity. In addition, germline B...

Velicer(C M),Taplin(S) Genet Med 2001-08-09

...BRCA1/2 knowledge, genetic testing intentions, and communication patterns in breast cancer survivors (survivors).,A popu...

Gad(S),Aurias(A),Puget(N),Mairal(A),Schurr... Genes Chromosomes Cancer 2001-06-14

...BRCA1 gene are responsible for the majority of hereditary breast and ovarian cancers. BRCA1 germline mutations, however,...

Kuschel(B),Gayther(S A),Easton(D F),Ponder... Genes Chromosomes Cancer 2001-06-14

We report an apparent BRCA1 homozygous knockout that, on further analysis, was found to be an artefact of the polymerase...

Hashizume(R),Fukuda(M),Maeda(I),Nishikawa(... J Biol Chem 2001-06-28

...BRCA1. Whereas individually BRCA1 and BARD1 have very low ubiquitin ligase activities in vitro, BRCA1 combined with BARD...

Chappuis(P O),Ghadirian(P),Foulkes(W D) Cancer Invest 2001-04-19

...BRCA1/2 and CDKN2A. Whether or not a true site-specific pancreatic adenocarcinoma syndrome exists is not known. The real...

Gentile(M),Wiman (A),Thorstenson(S),Loman(... Int J Cancer 2001-04-26

...BRCA1 or BRCA2 gene alterations (n = 32, ages 28 to 40 years). Among the consecutive patients, extensive LOH was observe...

Krajinovic(M),Ghadirian(P),Richer(C),Sinne... Int J Cancer 2001-04-26

...BRCA1 and BRCA2 as well as reproductive history constitute only 30% of the cause, environmental exposure may play a sign...

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