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TP53 BRCA1 CRISPR single-cell cancer

Osin(P P),Lakhani(S R) Breast Cancer Res 2001-06-21

...BRCA1-associated breast cancer is accumulating. BRCA1-associated tumours appear to show an increased frequency of TP53 m...

Bertwistle(D),Ashworth(A) Breast Cancer Res 2001-06-21

...BRCA1 could lead to inappropriate proliferation, consistent with the high mitotic grade of BRCA1-associated tumours. BRC...

Lalloo(F),Evans(D G) Breast Cancer Res 2001-06-21

Approximately 5% of all breast cancers are due to one of the high-risk breast cancer genes BRCA1 and BRCA2, or possibly ...

Obermiller(P S),Tait(D L),Holt(J T) Breast Cancer Res 2001-07-05

...BRCA1. Because mutational inactivation of gene function is specific to tumor cells in these settings, cancer gene correc...

Neuhausen(S L) Breast Cancer Res 2001-07-05

...BRCA1 and BRCA2. For genetic screening of a population with a founder mutation, testing can be targeted to the mutation,...

Yu(V) Breast Cancer Res 2001-07-05

Inheritance of germline BRCA1 mutations is associated with a high risk of breast and ovarian cancers. A multitude of cel...

Eeles(R A) Breast Cancer Res 2001-07-19

...BRCA1 and BRCA2 germline status. Carriers of BRCA1 and BRCA2 mutations are relatively rare, so the strategies for manage...

Scully(R) Breast Cancer Res 2001-07-05

...BRCA1 and BRCA2, appear to participate in a common pathway that is involved in the control of homologous recombination a...

Gardner(K),Liu(E T) Breast Cancer Res 2001-05-10

Recent work by Mak et al demonstrates that mice carrying a T-cell-specific disruption of the brca1 gene display markedly...

Bernard-Gallon(D J),Déchelotte(P),Vissac(C... Breast Cancer Res 2001-05-10

BRCA1 and BRCA2 breast cancer susceptibility genes encode proteins, the normal cellular functions of which are complex a...

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