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Germline BRCA1 mutations in Iranian women with breast cancer.

Ghaderi(A),Talei(A),Farjadian(S),Mosalaei(... Cancer Lett 2001-04-26

BRCA1 is known as a familial early onset breast cancer gene located in the long arm of chromosome 17. Alterations in thi...

Occult carcinoma in prophylactic oophorectomy specimens: prevalence and assoc...

Colgan(T J),Murphy(J),Cole(D E),Narod(S),R... Am J Surg Pathol 2001-12-04

...BRCA1 mutation positive, showed occult carcinoma of the ovaries and/or in situ or invasive carcinoma of a fallopian tube...

Solution structure and backbone dynamics of the human DNA ligase IIIalpha BRC...

Krishnan(V V),Thornton(K H),Thelen(M P),Co... Biochemistry 2001-12-07

...BRCA1 carboxyl terminus) domains are found in a number of DNA repair enzymes and cell cycle regulators and are believed ...

Breast cancer epidemiology, prevention, and early detection.

Brewster(A),Helzlsouer(K) Curr Opin Oncol 2001-12-26

...BRCA1 or BRCA2, prophylactic oophorectomy and bilateral mastectomy have emerged as preventative surgical options that ca...

BRCA1 and GADD45 mediated G2/M cell cycle arrest in response to antimicrotubu...

Mullan(P B),Quinn(J E),Gilmore(P M),McWill... Oncogene 2001-11-01

BRCA1 is a tumour suppressor gene implicated in the predisposition to early onset breast and ovarian cancer. We have gen...

Progesterone receptor variant increases ovarian cancer risk in BRCA1 and BRCA...

Runnebaum(I B),Wang-Gohrke(S),Vesprini(D),... Pharmacogenetics 2001-12-26

...BRCA1 and BRCA2 carriers with a prior diagnosis of ovarian cancer, 392 carriers with a diagnosis of breast cancer and 24...

Inhibition of BRCA1 leads to increased chemoresistance to microtubule-interfe...

Lafarge(S),Sylvain(V),Ferrara(M),Bignon(Y ... Oncogene 2001-11-01

...BRCA1 expression, as determined by real-time quantitative PCR and by Western blotting. Decreased expression of BRCA1 led...

Repair of DNA interstrand cross-links.

Dronkert(M L),Kanaar(R) Mutat Res 2001-10-04

...Brca1 and Brca2, the Fanconi anemia-associated FANC proteins, and cell cycle checkpoint proteins are involved in regulat...

Association and aggregation analysis using kin-cohort designs with applicatio...

Chatterjee(N),Shih(J),Hartge(P),Brody(L),T... Genet Epidemiol 2001-11-01

When a rare inherited mutation in a disease gene, such as BRCA1, is found through extensive study of high-risk families,...

Increased frequency of ATM mutations in breast carcinoma patients with early ...

Teraoka(S N),Malone(K E),Doody(D R),Suter(... Cancer 2001-08-30

...BRCA1 or BRCA2, and 81 were from matched controls.,A total of 12 individuals with ATM mutations were identified, 11 amon...

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