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Functional analysis of CpG methylation in the BRCA1 promoter region.

DiNardo(D N),Butcher(D T),Robinson(D P),Ar... Oncogene 2001-09-27

...BRCA1 promoter and to clarify the functional status of the BRCA1 CRE (cAMP response element) motif. Luciferase reporter ...

p38 mitogen-activated protein kinase-independent induction of gadd45 expressi...

Chou(T T),Trojanowski(J Q),Lee(V M) J Biol Chem 2001-12-07

...BRCA1 may be a potential mechanism whereby NGF regulates pleiotropic responses.

Impact of educational print materials on knowledge, attitudes, and interest i...

Schwartz(M D),Benkendorf(J),Lerman(C),Isaa... Cancer 2001-09-20

...BRCA1/BRCA2 founder mutations among Ashkenazi Jewish individuals has led to increased salience of BRCA1/BRCA2 testing fo...

Advances in the management of epithelial ovarian cancer.

Memarzadeh(S),Berek(J S) J Reprod Med 2001-12-07

...BRCA1 and BRCA2. Known risk factors for ovarian cancer include nulliparity and a strong family history of ovarian cancer...

Risk of breast and ovarian cancer in women with strong family histories.

Srivastava(A),McKinnon(W),Wood(M E) Oncology (Williston Park) 2001-12-05

...BRCA1, BRCA2, and TP53. Moderate-risk genes associated with syndromes that are inherited in an autosomal dominant patter...

Adenosine nucleotide modulates the physical interaction between hMSH2 and BRCA1.

Wang(Q),Zhang(H),Guerrette(S),Chen(J),Mazu... Oncogene 2001-08-23

...BRCA1-interacting protein, was also found to interact with hMSH2. In addition, BRCA1 was found to associate with both hM...

Genetic susceptibility for breast cancer--risk assessment and counseling.

Ang(P),Garber(J E) Semin Oncol 2001-08-30

...BRCA1 and BRCA2 mutation carriers, and discuss some of the counseling issues that may occur as physicians and patients e...

Disruption of BRCA1 LXCXE motif alters BRCA1 functional activity and regulati...

Fan(S),Yuan (R),Ma(Y X),Xiong(J),Meng(Q),E... Oncogene 2001-09-06

...BRCA1 and RB proteins was observed. Over-expression of wild-type BRCA1 (wtBRCA1) did not cause cell cycle arrest but did...

BRCA1 RING domain cancer-predisposing mutations. Structural consequences and ...

Brzovic(P S),Meza(J E),King(M C),Klevit(R ... J Biol Chem 2001-12-07

...BRCA1 RING domain and their effect on the interaction with the BARD1 RING domain. Each of the BRCA1 Site II mutants stil...

Breast cancer.

Kuter(I) Oncologist 2001-10-18

...BRCA1, mutations. Two important presentations re-analyzed the outcome of the pivotal trials using Herceptin to treat met...

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