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TP53 BRCA1 CRISPR single-cell cancer

Ruffner(H),Joazeiro(C A),Hemmati(D),Hunter... Proc Natl Acad Sci U S A 2001-05-21

...BRCA1-null human breast cancer cells, HCC1937. Additionally, these mutations within the BRCA1 RING domain are not capabl...

Cavanaugh(J), Am J Hum Genet 2001-06-07

...BRCA1 and BRCA2, most attempts have failed to produce replicable linkage findings. For example, in multiple sclerosis an...

Esteller(M),Corn(P G),Baylin(S B),Herman(J G) Cancer Res 2001-05-10

...BRCA1, hMLH1, GSTP1, MGMT, CDH1, TIMP3, and DAPK), each rigorously characterized for association with abnormal gene sile...

Buller(R E),Lallas(T A),Shahin(M S),Sood(A... Clin Cancer Res 2001-06-14

...BRCA1-related hereditary breast cancers suggest that both unique and specific BRCA1-associated p53 mutations may be foun...

Di Prospero(L S),Seminsky(M),Honeyford(J),... CMAJ 2001-05-03

...BRCA1 and BRCA2 genes. The purpose of our study was to explore how genetic testing had affected people found to have a B...

Slebos(R J),Taylor(J A) Biochem Biophys Res Commun 2001-04-05

...BRCA1 and -2 are involved in the proper control of homologous recombination, suggesting a role of this type of repair in...

Risch(H A),McLaughlin(J R),Cole(D E),Rosen... Am J Hum Genet 2001-04-05

...BRCA1, with denaturing gradient gel electrophoresis for the remainder of BRCA1, and with PTT for exons 10 and 11 of BRCA...

Speit(G),Trenz(K),Schütz(P),Bendix(R),Dörk(T) Cytogenet Cell Genet 2001-03-29

...BRCA1 cells, thus indicating a difference in the pathways leading to mutagen sensitivity in cells with a BRCA1 or an AT ...

Julian-Reynier(C),Sobol(H),Sévilla(C),Nogu... Psychooncology 2001-03-01

Due to the technical difficulties involved in identifying BRCA1/2 genetic mutations, the affected patients have to be in...

Moore(D F),Chatterjee(N),Pee(D),Gail(M H) Genet Epidemiol 2001-04-05

...BRCA1 or BRCA2 was 0.56, a figure that was lower than previously estimated from highly affected families. The method tha...

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