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TP53 BRCA1 CRISPR single-cell cancer

Zheng(L),Annab(L A),Afshari(C A),Lee(W H),... Proc Natl Acad Sci U S A 2001-09-20

...Brca1-proficient cells. Ectopic expression in Brca1-deficient cells of wild-type BRCA1, but not clinically validated BRC...

Angèle(S),Tanière(P),Hall(J) Bull Cancer 2001-09-27

...BRCA1, BRCA2 and TP53. Genes of low penetrance, frequently mutated in the general population, might play an important ro...

Lassetn(C),Bonadona(V) Bull Cancer 2001-09-27

Women identified or suspected as carriers of mutations in BRCA1 or BRCA2 susceptibility genes have a high risk to develo...

Chiba(N),Parvin(J D) J Biol Chem 2001-12-04

...BRCA1 protein is known to participate in multiple cellular processes. In these experiments, we resolved four distinct BR...

Loman(N),Johannsson(O),Kristoffersson(U),O... J Natl Cancer Inst 2001-09-20

BRCA1 and BRCA2 are the two major susceptibility genes involved in hereditary breast cancer. This study was undertaken t...

Kachhap(S K),Ghosh(S N) Indian J Exp Biol 2001-10-25

Breast cancer susceptibility gene (BRCA1) is known to be responsible for hereditary breast and ovarian cancer. This gene...

Smith(S A),Richards(W E),Caito(K),Hanjani(... Gynecol Oncol 2001-12-28

...BRCA1 germline alterations by single-strand conformation polymorphism analysis.,Protein-truncating mutations in BRCA1 we...

Phillips(J L),Hayward(S W),Wang(Y),Vassell... Cancer Res 2001-12-12

...BRCA1, and CTNNA, which showed decreased expression. Thirty % of expression changes occurred in regions the genomic copy...

de Bock(G H),Tollenaar(R A),Papelard(H),Co... Br J Cancer 2001-12-11

Thus far, studies investigating the differences in tumour characteristics between breast cancer in BRCA1-carriers and ot...

Kataoka(A),Tada(M),Yano(M),Furuuchi(K),Cor... Am J Pathol 2001-12-04

...BRCA1, APC, hMSH6, and E-cadherin genes, and successfully detected mutations in mRNA and genomic DNA. Because this metho...

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