Since the cloning of BRCA1 and BRCA2, genetic testing for breast and ovarian cancer susceptibility has become more wides...
...BRCA1 mutation, whereas no mutation in BRCA2 was found. Approximately, two-thirds of the BRCA1 mutation carriers had one...
...BRCA1, and CTNNA, which showed decreased expression. Thirty % of expression changes occurred in regions the genomic copy...
Thus far, studies investigating the differences in tumour characteristics between breast cancer in BRCA1-carriers and ot...
...BRCA1 mutation positive, showed occult carcinoma of the ovaries and/or in situ or invasive carcinoma of a fallopian tube...
...BRCA1 carboxyl terminus) domains are found in a number of DNA repair enzymes and cell cycle regulators and are believed ...
...BRCA1 germline alterations by single-strand conformation polymorphism analysis.,Protein-truncating mutations in BRCA1 we...
...BRCA1 as the probe. The human SRBC gene (hSRBC) was mapped to chromosome region 11p15.5-p15.4, close to marker D11S1323,...
...BRCA1-CtIP complex in turn modulates the transcription of DNA-damage-response genes. We have shown that the BRCA1-bindin...
...BRCA1 and BRCA2. Breast tumors of patients with germ-line mutations in the BRCA1 and BRCA2 genes have more genetic defec...
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