...BRCA1 protein generated by in vitro translation interacts with gamma-tubulin. A specific domain of BRCA1 protein, BRCA1 ...
...BRCA1, or NBS1 genes were detected. These results confirm ATR, MED1, and CHK1 as targets of the mutator pathway in stoma...
The vast majority of familial ovarian cancers harbor a germline mutation in either the breast cancer gene BRCA1 or BRCA2...
...BRCA1-2 mutation carriers.,Germline BRCA1-2 mutations are common in non-Ashkenazi families with a member having double p...
...BRCA1 or BRCA2, prophylactic oophorectomy and bilateral mastectomy have emerged as preventative surgical options that ca...
...BRCA1 and BRCA2 carriers with a prior diagnosis of ovarian cancer, 392 carriers with a diagnosis of breast cancer and 24...
...BRCA1 mutations as an example. The main conclusions are the following: (1) The relative risk ratio of the risks of radia...
...BRCA1 and BRCA2 account for approximately 50% of breast cancer families with more than four affected cases, whereas exon...
...BRCA1 (n=98; 19%) or BRCA2 (n=21; 4%). BRCA1/2 mutations were found in 72 (52%) of 138 families with breast and ovarian ...
Three founder mutations in the cancer-associated genes BRCA1 and BRCA2 occur frequently enough among Ashkenazi Jews to w...
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