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BRCA1/BRCA2 germline mutations in locally recurrent breast cancer patients af...

Turner(B C),Harrold(E),Matloff(E),Smith(T)... J Clin Oncol 2000-01-04

...BRCA1 or BRCA2 (BRCA1/2) mutations, the outcome of treatment with LRT with respect to IBTR has not been determined. In t...

An evaluation of needs of female BRCA1 and BRCA2 carriers undergoing genetic ...

Metcalfe(K A),Liede(A),Hoodfar(E),Scott(A)... J Med Genet 2000-12-07

...BRCA1/2 and to determine the impact of receiving a positive BRCA1/2 result. This is the first study to report on a large...

Sequence-specific transcriptional corepressor function for BRCA1 through a no...

Zheng(L),Pan(H),Li(S),Flesken-Nikitin(A),C... Mol Cell 2000-12-07

...BRCA1. ZBRK1 represses transcription through this recognition sequence in a BRCA1-dependent manner. These results thus r...

Histology of prophylactically removed ovaries from BRCA1 and BRCA2 mutation c...

Casey(M J),Bewtra(C),Hoehne(L L),Tatpati(A... Gynecol Oncol 2000-09-25

...BRCA1 and BRCA2 mutation status had been tested were selected from our database. Thirty had tested positive for BRCA1 mu...

Regional methylation of the 5' end CpG island of BRCA1 is associated with red...

Magdinier(F),Billard(L M),Wittmann(G),Frap... FASEB J 2000-08-25

...BRCA1 does not seem to be related to BRCA1 gene alterations. Southern blot analysis and the bisulfite sequencing method ...

Cyclosporine A inhibition of prolactin-dependent up-regulation of BRCA1 prote...

Favy(D A),Rio(P G),Vissac(C),Maurizis(J C)... Anticancer Res 2000-08-17

...BRCA1 protein expression in vitro.,The expression of BRCA1 was monitored in a human breast cancer cell line (MCF7) by co...

Prophylactic mastectomy or screening in women suspected to have the BRCA1/2 m...

Unic(I),Verhoef(L C),Stalmeier(P F),van Da... Med Decis Making 2000-11-29

...BRCA1/2 mutation may choose between two management options: breast cancer screening and prophylactic mastectomy (PM).,To...

Over-expression of wild-type Rad51 correlates with histological grading of in...

Maacke(H),Opitz(S),Jost(K),Hamdorf(W),Henn... Int J Cancer 2000-12-22

Breast cancer is a major cause of cancer-related death in women. BRCA1 tumour-suppressor function is abolished in sporad...

In search of the tumour-suppressor functions of BRCA1 and BRCA2.

Scully(R),Livingston(D M) Nature 2000-12-28

...BRCA1 and BRCA2 (ref. 1). Each gene product interacts with recombination/DNA repair proteins in pathways that participat...

Differential effects of theaflavin monogallates on cell growth, apoptosis, an...

Lu(J),Ho(C T),Ghai(G),Chen(K Y) Cancer Res 2000-12-22

...BRCA1, BRCA2, and Cox-1, were not significantly affected by TF-2. These findings suggest that TF-2 may be responsible, a...

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