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TP53 BRCA1 CRISPR single-cell cancer

Tõnisson(N),Kurg(A),Kaasik(K),Lõhmussaar(E... Clin Chem Lab Med 2000-09-18

...BRCA1 gene and single nucleotide polymorphism (SNP) chip for genotyping were used as a model system. Chip surface chemis...

Sekine(M),Tanaka(K) Nihon Rinsho 2000-10-19

...BRCA1 and BRCA2 are reported to account for around 50% of familial ovarian cancer families. In this paper, we describe t...

Meng(Q),Gao(B),Goldberg(I D),Rosen(E M),Fa... Biochem Biophys Res Commun 2000-08-17

...BRCA1 expression. In addition, an enhanced expression of BRCA1 significantly blocked alcohol-stimulated cell invasion. T...

Khoo(U S),Ngan(H Y),Cheung(A N),Chan(K Y),... Hum Mutat 2000-08-25

...BRCA1 and BRCA2 mutations in women with ovarian cancer unselected for family history. The contribution of BRCA1 and BRCA...

Ashida(A),Fukutomi(T),Tsuda(H),Akashi-Tana... Jpn J Clin Oncol 2000-05-02

...BRCA1 gene (exon5) was detected. The patient has been well since the operation (10 months). These findings may provide u...

Esteller(M),Silva(J M),Dominguez(G),Bonill... J Natl Cancer Inst 2000-05-12

...BRCA1 locus and loss of BRCA1 protein in tumors. To address whether BRCA1 may be inactivated by pathways other than muta...

Ozer(E),Sis(B),Ozen(E),Sakizli(M),Canda(T)... Appl Immunohistochem Mol Mo... 2000-09-06

...BRCA1 expression was found in five cases (14.3%). Statistical analysis showed that loss of BRCA1 expression was signific...

Favy(D A),Rio(P G),Vissac(C),Maurizis(J C)... Anticancer Res 2000-08-17

...BRCA1 protein expression in vitro.,The expression of BRCA1 was monitored in a human breast cancer cell line (MCF7) by co...

Bochar(D A),Wang(L),Beniya(H),Kinev(A),Xue... Cell 2000-09-14

...BRCA1 is associated with a SWI/SNF-related complex. We show that BRCA1 can directly interact with the BRG1 subunit of th...

Kainu(T),Juo(S H),Desper(R),Schaffer(A A),... Proc Natl Acad Sci U S A 2000-09-19

A significant proportion of familial breast cancers cannot be explained by mutations in the BRCA1 or BRCA2 genes. We app...

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