...BRCA1 or BRCA2 mutations that impair homologous recombination repair. While recent studies have clarified the key roles ...
...BRCA1-associated protein-1 (BAP1), have been recognized as common in ccRCC. Although these genomic alterations are centr...
...BRCA1 binding sites (BBS) were identified within this promoter region. Subsequent experimental results suggest that BRCA...
...BRCA1 and BRCA2, represents a critical tool for precision oncology, enabling individualized risk stratification and the ...
...BRCA1, TOP2A, BRCA2, BUB1B, HSP90AA1, PLK4, and EDIL3), with EDIL3 showing the greatest increase in BA. EDIL3 is located...
...BRCA1-associated SGTs. We report a Colombian family segregating the BRCA1 c.3331_3334delCAAG (p.Gln1111Asnfs*5) founder ...
...BRCA1/2, TP53, PTEN, CHEK2, PALB2, and others) was negative, excluding hereditary predisposition. Tumor profiling confir...
...BRCA1, DNMT1, EZH2, PTTG1, SND1, UHRF1). APEX1 was downregulated in CRC, while the other six were upregulated. The diagn...
...BRCA1/BRCA2 mutation, primary treatment, and surgical outcome are strong independent prognostic factors of overall survi...
...BRCA1) by signal recovery after removing a black hole quencher (BHQ) linked DNA, showing a wide linear range from 1.0 pM...
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