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[The coexistence of breast and ovarian cancer in patient with insertion-dupli...

Zubelewicz-Szkodzińska(B),Braczkowski(R) Wiad Lek 2000-10-04

...BRCA1 gene.

Why are the majority of hereditary cases of early-onset breast cancer sporadi...

Cui(J),Hopper(J L) Cancer Epidemiol Biomarkers... 2000-12-07

...BRCA1 or BRCA2 do not report a family history of the disease. That is, the majority of "hereditary" cases are "sporadic....

1alpha,25-Dihydroxyvitamin D3 down-regulates estrogen receptor abundance and ...

Swami(S),Krishnan(A V),Feldman(D) Clin Cancer Res 2000-12-28

...BRCA1) protein is reduced by 1,25(OH)2D3 treatment. Overall, these results suggest that the antiproliferative effects of...

Breast cancer: genetics, risks, and strategies.

Nogueira(S M),Appling(S E) Nurs Clin North Am 2000-10-12

...BRCA1 and BRCA2 genes and related research has increased our understanding of key risk factors. After identifying those ...

Prevention and therapy for BRCA1/2 mutation carriers and women at high risk f...

Kuschel(B),Lux(M P),Goecke(T O),Beckmann(M W) Eur J Cancer Prev 2000-12-21

...BRCA1 and BRCA2. Germline mutations of the cancer-susceptibility genes BRCA1 and BRCA2 seem to be the major aetiology of...

Transcriptional repression of BRCA1 by aberrant cytosine methylation, histone...

Rice(J C),Futscher(B W) Nucleic Acids Res 2000-10-30

...BRCA1 promoter compared to non-methylated BRCA1 expressing cells. The chromatin of the methylated UACC3199 BRCA1 promote...

Methylation of the BRCA1 promoter is associated with decreased BRCA1 mRNA lev...

Rice(J C),Ozcelik(H),Maxeiner(P),Andrulis(... Carcinogenesis 2000-10-02

...BRCA1 is an important mechanism involved in breast cancer pathogenesis. Mutation is often responsible for BRCA1 inactiva...

Abnormal expression of BRCA1 and BRCA1-interactive DNA-repair proteins in bre...

Yoshikawa(K),Ogawa(T),Baer(R),Hemmi(H),Hon... Int J Cancer 2000-09-26

...BRCA1 is rare, BRCA1 protein expression is reduced in about 30% of sporadic breast carcinomas (Yoshikawa et al., Clin. C...

BRCA1 activation of the GADD45 promoter.

Jin(S),Zhao(H),Fan(F),Blanck(P),Fan(W),Col... Oncogene 2000-09-14

...BRCA1. In contrast, both the tumor-derived BRCA1 mutants (p1749R and Y1853insA) and truncated BRCA1 mutant protein (Delt...

Familial cancer risks to offspring from mothers with 2 primary breast cancers...

Hemminki(K),Vaittinen(P),Easton(D) Int J Cancer 2000-09-26

...BRCA1 and BRCA2 genes, while the risk of soft tissue and bone sarcomas may reflect the association of these tumours with...

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