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TP53 BRCA1 CRISPR single-cell cancer

Yamamoto(R R),Axton(J M),Yamamoto(Y),Saund... Genetics 2000-11-30

...BRCA1 C terminus) domain superfamily of proteins implicated in DNA repair and cell cycle checkpoint control. Mus101, whi...

Pierce(L J),Strawderman(M),Narod(S A),Oliv... J Clin Oncol 2000-10-25

Recent laboratory data suggest a role for BRCA1/2 in the cellular response to DNA damage. There is a paucity of clinical...

Kozlowski(P),Sobczak(K),Jasinska(A),Krzyzo... Hum Mutat 2000-10-27

One of the unclassified variants of the BRCA1 gene which has drawn considerable attention in recent years is the 12-bp i...

Leong(T),Whitty(J),Keilar(M),Mifsud(S),Ram... Int J Radiat Oncol Biol Phy... 2000-12-07

...BRCA1 and BRCA2, using various methods including protein truncation testing, direct DNA sequencing, and a PCR-based BRCA...

Peelen(T),de Leeuw(W),van Lent(K),Morreau(... Int J Cancer 2000-11-30

Mutations in the BRCA1 gene cause strongly elevated risks of breast and ovarian cancers but may also confer a 3-fold inc...

Tian(H),Brody(L C),Mao(D),Landers(J P) Anal Chem 2000-12-15

...BRCA1). For capillary coating, allyldimethylchlorosilane, 4-chlorobutyldimethylchlorosilane, (gamma-methacryloxypropyl)t...

Fan(S),Meng(Q),Gao(B),Grossman(J),Yadegari... Cancer Res 2000-11-08

...BRCA1, a potent inhibitor of ER-alpha activity, and, in part, by a modest increase in the ER-alpha levels. Our findings ...

Bachelier(R),Dalla Venezia(N),Mazoyer(S),F... Int J Cancer 2000-12-08

...BRCA1 gene have been extensively studied but little is known about murine BRCA1 proteins. To better characterize these p...

Hegde(M R),Chong(B),Fawkner(M J),Leary(J),... Hum Mutat 2000-11-21

The identification of mutations in the BRCA1 gene poses difficulties in achieving a screening outcome that satisfies the...

Wang(P H),Shyong(W Y),Li(Y F),Lee(H H),Tsa... Jpn J Clin Oncol 2000-11-03

Germline BRCA1 mutations of sporadic ovarian cancers are presumed to be rare events, except among specific populations. ...

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