...BRCA1 and BRCA2 genes, while the risk of soft tissue and bone sarcomas may reflect the association of these tumours with...
...BRCA1 and BRCA2. Germline mutations of the cancer-susceptibility genes BRCA1 and BRCA2 seem to be the major aetiology of...
...BRCA1 promoter compared to non-methylated BRCA1 expressing cells. The chromatin of the methylated UACC3199 BRCA1 promote...
...BRCA1 represents a unique opportunity to search for such premalignant alterations in ovarian tissues that are at unusual...
...BRCA1 predispose women to breast and ovarian cancers. BRCA1 contains several functional domains that interact directly o...
...BRCA1 predispose to breast and ovarian cancer. Most germline BRCA1 mutations are small insertions, deletions, or single ...
...BRCA1 expression was found in five cases (14.3%). Statistical analysis showed that loss of BRCA1 expression was signific...
...BRCA1 is associated with a SWI/SNF-related complex. We show that BRCA1 can directly interact with the BRG1 subunit of th...
A significant proportion of familial breast cancers cannot be explained by mutations in the BRCA1 or BRCA2 genes. We app...
...BRCA1 or BRCA2 do not report a family history of the disease. That is, the majority of "hereditary" cases are "sporadic....
山东省济南市章丘区文博路2号
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