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TP53 BRCA1 CRISPR single-cell cancer

Gatei(M),Scott(S P),Filippovitch(I),Soroni... Cancer Res 2000-07-20

...BRCA1, a tumor suppressor gene. BRCA1 is a nuclear protein with a cell cycle-regulated expression pattern and is hyperph...

Meng(Q),Qi(M),Chen(D Z),Yuan(R),Goldberg(I... J Mol Med (Berl) 2000-10-24

...BRCA1 expression. Our current finding is the first demonstration that I3C can activate the function of invasion suppress...

Sutcliffe(S),Pharoah(P D),Easton(D F),Pond... Int J Cancer 2000-07-13

...BRCA1 and BRCA2, the ovarian cancer risk was 11.59 (3.12-29.7) and that of breast cancer 3.32 (1.52-6.31). As well as ha...

MacLachlan(T K),Dash(B C),Dicker(D T),El-D... J Biol Chem 2000-11-13

...BRCA1 in response to adriamycin. Ectopic expression of p53 resulted in a rapid decrease in BRCA1 protein and RNA levels ...

Nagasawa(K),Kitamura(K),Yasui(A),Nimura(Y)... J Biol Chem 2000-11-13

...BRCA1 COOH terminus (BRCT) motif is present in many nuclear proteins that contribute to cell cycle regulation or DNA rep...

Huang(L W),Garrett(A P),Schorge(J O),Muto(... Am J Clin Pathol 2000-07-19

...BRCA1-related and BRCA1-unrelated PSCP cases. The high LOH rate identified on 6q, 9p, 17p, 17q, and Xq in PSCP suggests ...

Meijers-Heijboer(E J),Verhoog(L C),Brekelm... Lancet 2000-07-20

...BRCA1 and BRCA2 genes highly predispose to breast and ovarian cancer. In families with BRCA1 or BRCA2 mutations, identif...

Gershoni-Baruch(R),Dagan(E),Fried(G),Bruch... Eur J Cancer 2000-07-27

...BRCA1 (185delAG and 5382insC) and BRCA2 (6174delT). The study cohort was composed of 172 women diagnosed with breast can...

Niwa(Y),Oyama(T),Nakajima(T) Jpn J Cancer Res 2000-07-18

...BRCA1 in sporadic breast cancers, the relationship between DNA methylation of the BRCA1 promoter region and BRCA1 expres...

Shen(D),Wu(Y),Chillar(R),Vadgama(J V) Anticancer Res 2000-05-31

...BRCA1 mutation could be detected in diverse types of cancers. We used PCR-NIRCA and PCR-SSCP methods for screening the B...

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