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Denaturing high-performance liquid chromatography detects reliably BRCA1 and ...

Wagner(T),Stoppa-Lyonnet(D),Fleischmann(E)... Genomics 2000-03-02

...BRCA1 and BRCA2 were tested. Second, 25 index individuals with complete DHPLC analysis of BRCA1 were reanalyzed by dye-t...

BRCA1 effects on the cell cycle and the DNA damage response are linked to alt...

MacLachlan(T K),Somasundaram(K),Sgagias(M)... J Biol Chem 2000-02-29

...BRCA1 using an adenovirus vector (Ad-BRCA1) leads to dephosphorylation of the retinoblastoma protein accompanied by a de...

Risk models for familial ovarian and breast cancer.

Antoniou(A C),Gayther(S A),Stratton(J F),P... Genet Epidemiol 2000-04-18

...BRCA1 and BRCA2 mutations were estimated to be 0. 00128 and 0.00172, respectively. Our results suggest that BRCA1 and BR...

Genetic alterations in 'normal' luminal and myoepithelial cells of the breast...

Lakhani(S R),Chaggar(R),Davies(S),Jones(C)... J Pathol 2000-02-14

...BRCA1 gene exhibited LOH on 17q in 3/33 normal clones. One of these clones showed loss of wild-type allele indicating ge...

MALDI-TOF based mutation detection using tagged in vitro synthesized peptides...

Garvin(A M),Parker(K C),Haff(L) Nat Biotechnol 2000-02-29

...BRCA1 were readily identified using this method. The process can be multiplexed and is amenable to automation, providing...

Dual immunofluorescence labeling with cell-specific markers localizes BRCA1 i...

Daniel(D C) Cell Tissue Res 2000-02-09

...BRCA1 was used for colabeling with each of these markers. Epifluorescence microscopy revealed BRCA1 immunoreactivity in ...

Screening for BRCA2 mutations in 81 Dutch breast-ovarian cancer families.

Peelen(T),van Vliet(M),Bosch(A),Bignell(G)... Br J Cancer 2000-01-31

...BRCA1 revealed that in our study-population of 81 families, 15 families were segregating either the exon 13 or exon 22 d...

Lack of the predominant BRCA1 and BRCA2 mutations in Jewish ovarian carcinoma...

Menczer(J),Lerner-Geva(L),Sade-Bruchim(R B... Eur J Gynaecol Oncol 2000-01-18

...BRCA1 and BRCA2 mutations in archival paraffin-embedded tumor tissue of four Jewish women with ovarian carcinoma who pre...

BRCA1 mutation testing for Japanese patients with ovarian cancer in breast ca...

Yamashita(Y),Sagawa(T),Fujimoto(T),Sugawar... Breast Cancer Res Treat 2000-02-10

...BRCA1. These characteristics may assist physicians in selecting BRCA1 mutation testing for ovarian cancer patients. The ...

[Molecular biology of ovarian cancer].

Tanaka(K) Gan To Kagaku Ryoho 2000-01-27

...BRCA1 is thought to be the most likely candidate for having a causal relation with the familial ovarian cancer syndrome.

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