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Trends in the Utilization of BRCA1 and BRCA2 Testing After the Introduction o...

Dossa(F),Baxter(NN),Sutradhar(R),Little(T)... Curr Oncol 2025-08-06

...BRCA1/BRCA2 testing use after implementation of a publicly funded testing program. We conducted a retrospective, near po...

What Happens After Menopause (WHAM)? A Progress Report of a Prospective Contr...

Price(SAL),Maki(PM),El Khoudary(SR),Brand(... BJOG 2025-07-23

...BRCA1/2 pathogenic variants undergoing RRSO and 102 age-matched comparators who retained their ovaries. Outcomes includi...

Pathologic complete response after neoadjuvant chemotherapy for HER-2 negativ...

Chen(X),Ji(L),Fan(Y),Li(Q),Li(Q),Wang(J),L... Future Oncol 2025-08-00

...BRCA1/2. This retrospective cohort study included HER-2-negative breast cancer patients who completed HRR genetic testin...

Molecular features of TNBC govern heterogeneity in the response to radiation ...

Fischer(P),Schmid(M),Ohradanova-Repic(A),S... Cell Death Dis 2025-07-21

...BRCA1-mutated MDA-MB-436 cells, C-ion irradiation was more potent compared to X-rays in inducing the NF-κB-driven immuno...

Mutational Profiling Detection in FNAC Samples of Different Types of Thyroid ...

Liang(R),Luo(M),Yang(X),Luo(B),Liu(R) Cancers (Basel) 2025-07-23

...BRCA1/2 (4.41%) and RAS (4.41%). Patients were categorized into BRAF-like (830 cases), RAS-like (36 cases), high-risk mu...

Functional Disruption of IQGAP1 by Truncated PALB2 in Two Cases of Breast Can...

Pérez-Rodríguez(ND),Martín-Ramírez(R),Gonz... Biomedicines 2025-07-23

...BRCA1-PALB2-BRCA2 homologous recombination repair complex, are associated with increased risk and aggressiveness of brea...

Impact of germline BRCA1/2 status on outcomes for patients with HR+/HER2- met...

Bottosso(M),Zurlo(C),Miglietta(F),Cattelan... Breast 2025-10-00

...BRCA1/2 mutation (gBRCAm) carriers are HR+/HER2-. Sparse data suggest limited CDK4/6 inhibitors benefit among gBRCAm car...

Breast biopsies and breast cancer risk in Israeli BRCA germline pathogenic va...

Madorsky Feldman(D),Sklair-Levy(M),Laitman... Breast Cancer Res Treat 2025-10-00

...BRCA1 and BRCA2 pathogenic variants (PVs) carriers. Female BRCA1 and BRCA2 PV carriers treated at the Meirav Clinic, She...

Clinical utility and characteristics of comprehensive genomic profiling tests...

Terada(S),Tanaka(T),Hisamatsu(Y),Kita(M),T... Int J Clin Oncol 2025-10-00

...BRCA1/2, six for ERBB2, and five for PIK3CA. Twenty-five patients died before receiving their CGP results. The objective...

The use of hormonal contraceptives in a cohort of healthy women with BRCA mut...

Grandi(G),Sgandurra(A),Feliciello(L),Pedri... Eur J Contracept Reprod Hea... 2025-12-00

...BRCA1 vs. BRCA2), in comparison to similar women of the same cohort who were not using HC or had recently undergone risk...

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