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TP53 BRCA1 CRISPR single-cell cancer

Blesa(J R),Hernández-Yago(J) Biotechniques 2000-07-21

...BRCA1 and BRCA2, in which alterations span the entire gene. We have adapted the CSGE assay to a fluorescent platform--a ...

Gayther(S A),Pharoah(P D),Ponder(B A) J Mammary Gland Biol Neoplasia 2000-06-02

...BRCA1 and BRCA2 and summarize the cancer risks in women carrying a BRCA1 or BRCA2 mutation. We review the evidence for g...

Plon(S E) J Mammary Gland Biol Neoplasia 2000-06-02

...BRCA1 and BRCA2 in different clinical settings including at-risk individuals and cancer patients. The risk of breast can...

Chodosh(L A) J Mammary Gland Biol Neoplasia 2000-06-02

Current evidence strongly supports a role for the breast cancer susceptibility genes, BRCA1 and BRCA2, in both normal de...

Baer(R),Lee(W H) J Mammary Gland Biol Neoplasia 2000-06-02

The BRCA1 and BRCA2 genes encode large unrelated proteins that presumably function as tumor suppressors in normal epithe...

Sharan(S K),Bradley(A) J Mammary Gland Biol Neoplasia 2000-06-02

...Brca1 and Brca2 has greatly enhanced our knowledge of how BRCA1 and BRCA2 may function as tumor suppressors.

De Potter(C R),Coene(E D),Schelfhout(V R) J Mammary Gland Biol Neoplasia 2000-06-02

...BRCA1 should shed new light upon the exact localization of BRCA1.

Hakem(R),de la Pompa(J L),Mak(T W) J Mammary Gland Biol Neoplasia 2000-06-02

In humans, the inheritance of mutations in the breast cancer susceptibility genes BRCA1 and BRCA2 increases the risk of ...

Am J Hum Genet 2000-08-07

Recently, a 6-kb duplication of exon 13, which creates a frameshift in the coding sequence of the BRCA1 gene, has been d...

Robinson(M D),Chu(C E),Turner(G),Bishop(D ... Genet Test 2000-06-26

rearrangements have recently been identified in the BRCA1 gene. Inclusion of a method for identifying such rearrangement...

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