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Altered expression of BRCA1, BRCA2, and a newly identified BRCA2 exon 12 dele...

Rauh-Adelmann(C),Lau(K M),Sabeti(N),Long(J... Mol Carcinog 2000-09-26

Germline mutations of BRCA1 and BRCA2 predispose to hereditary breast, ovarian, and possibly prostate cancer, yet struct...

Hereditary breast cancer: a brief overview.

Sng(J H) Ann Acad Med Singapore 2000-12-28

...BRCA1 and BRCA2, amongst others.,In this brief overview, some of the advances in the aetiology of breast cancer will be ...

Prevalence of BRCA1 in a hospital-based population of Dutch breast cancer pat...

Papelard(H),de Bock(G H),van Eijk(R),Vliet... Br J Cancer 2000-09-28

The prevalence of disease-related BRCA1 mutations was investigated in 642 Dutch breast cancer patients not selected for ...

BRCA1 and BRCA2 mutations in Turkish breast/ovarian families and young breast...

Yazici(H),Bitisik(O),Akisik(E),Cabioglu(N)... Br J Cancer 2000-09-28

To date, BRCA1 and BRCA2 mutations in breast and/or ovarian patients have not been characterized in the Turkish populati...

Novel germline BRCA1 mutations detected in women in singapore who developed b...

Ho(G H),Phang(B H),Ng(I S),Law(H Y),Soo(K ... Cancer 2000-09-07

...BRCA1 has been extensively investigated, the contribution of inherited BRCA1 mutations to breast carcinoma in Asian popu...

Hereditary breast cancer: a review.

Arver(B),Du(Q),Chen(J),Luo(L),Lindblom(A) Semin Cancer Biol 2000-10-18

...BRCA1 and BRCA2 genes are known to predispose to breast and ovarian cancer in many families. Other genes are only involv...

BRCA1 facilitates stress-induced apoptosis in breast and ovarian cancer cell ...

Thangaraju(M),Kaufmann(S H),Couch(F J) J Biol Chem 2000-11-24

...BRCA1 in apoptosis, we examined the effect of wild-type and C-terminal-truncated dominant negative BRCA1 on breast and o...

Adaptive evolution of the tumour suppressor BRCA1 in humans and chimpanzees. ...

Huttley(G A),Easteal(S),Southey(M C),Tesor... Nat Genet 2000-08-28

Mutations in BRCA1 (ref. 1) confer an increased risk of female breast cancer. In a genome-wide scan of linkage disequili...

Absence of Brca2 causes genome instability by chromosome breakage and loss as...

Tutt(A),Gabriel(A),Bertwistle(D),Connor(F)... Curr Biol 2000-03-09

...BRCA1 and BRCA2 have a highly elevated risk of developing breast cancer [1]. BRCA1 and BRCA2 encode large proteins with ...

Specific H-Ras minisatellite alleles in breast cancer susceptibility.

Gosse-Brun(S),Sauvaigo(S),Daver(A),Page(M)... Anticancer Res 2000-03-23

...BRCA1 and BRCA2 genes account for the majority of familial aggregation of breast and ovarian cancers but other common ge...

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