...BRCA1 by IHC showed low levels of BRCA1 mRNA by RT-PCR.,BRCA1 expression paralleled cell proliferation in benign and bor...
...BRCA1 mutation. The current study examines the association between X-chromosome LOH and BRCA1 mutation.,Ninety tumor DNA...
...BRCA1 and BRCA2. We review the function of these different proteins, the incidence of mutations in their genes in carcin...
...BRCA1/2 mutations.,We used a simulated cohort of 30-year-old women who tested positive for BRCA1/2 mutations and constru...
...BRCA1 gene), and ESR (6q24-27/estrogen receptor gene). LOH of the TP53 marker was detected in 4 (44%) of 9 informative s...
...BRCA1 mutations retained a wild-type BRCA1 allele. The tumor with the somatic BRCA1 mutation contained a TP53 mutation a...
...BRCA1 (185delAG and 5382insC) and BRCA2 (6174delT) that account for the overwhelming majority of BRCA mutations in high-...
...BRCA1 or BRCA2 loci. BRCA2 is not likely to be a cancer-predisposing gene in this family because each sister inherited d...
...BRCA1 C-terminal domain that has been shown to mediate interactions of proteins involved in DNA repair. The induction of...
...BRCA1 and BRCA2 germline mutations. We aimed to establish whether pregnancy is a risk factor for hereditary breast cance...
山东省济南市章丘区文博路2号
齐鲁师范学院 genelibs生信实验室
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