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A novel human rad54 homologue, Rad54B, associates with Rad51.

Tanaka(K),Hiramoto(T),Fukuda(T),Miyagawa(K... J Biol Chem 2000-09-25

...BRCA1. These findings suggest that Rad54B may be functionally distinct from Rad54, although it may play an active role i...

Low penetrance genes associated with increased risk for breast cancer.

Weber(B L),Nathanson(K L) Eur J Cancer 2000-08-03

...BRCA1 and BRCA2, have been identified, and the prevalence and penetrance of mutations in these genes have been studied e...

Characteristics of BRCA1 mutations in a population-based case series of breas...

Anton-Culver(H),Cohen(P F),Gildea(M E),Zio... Eur J Cancer 2000-08-03

...BRCA1 mutations or 1.6% (95% CI: 0.8-2.9) among the 673 female breast cancer probands and 4 BRCA1 mutations or 3.3% (95%...

Incidence of BRCA1/2 germ line alterations in a high risk cohort participatin...

Klemp(J),Brady(D),Frank(T S),Kimler(B F),F... Eur J Cancer 2000-08-03

...BRCA1/2 gene sequencing, 3 declined. 26 (22%) of the 116 women had an alteration in BRCA1/2. Known deleterious mutations...

Ovarian cancer: epidemiology, biology, and prognostic factors.

Holschneider(C H),Berek(J S) Semin Surg Oncol 2000-08-23

...BRCA1 and BRCA2 tumor suppressor genes responsible for the majority of hereditary ovarian cancer. Additional risk factor...

Presymptomatic testing for BRCA1 and BRCA2: how distressing are the pre-test ...

Lodder(L N),Frets(P G),Trijsburg(R W),Meij... J Med Genet 2000-01-07

...BRCA1 and BRCA2 genes in 1994-1995. Healthy female mutation carriers have a high lifetime risk for breast cancer (56-87%...

Prevention with tamoxifen or other hormones versus prophylactic surgery in BR...

Grann(V R),Jacobson(J S),Whang(W),Hershman... Cancer J Sci Am 2000-03-13

...BRCA1/2 mutations.,We used a simulated cohort of 30-year-old women who tested positive for BRCA1/2 mutations and constru...

Allelic loss at the BRCA1, BRCA2 and TP53 loci in human sporadic breast carci...

Katsama(A),Sourvinos(G),Zachos(G),Spandido... Cancer Lett 2000-04-20

...BRCA1, BRCA2 and TP53 loci, in 82 sporadic breast carcinomas using a bank of highly polymorphic microsatellite markers l...

Specific H-Ras minisatellite alleles in breast cancer susceptibility.

Gosse-Brun(S),Sauvaigo(S),Daver(A),Page(M)... Anticancer Res 2000-03-23

...BRCA1 and BRCA2 genes account for the majority of familial aggregation of breast and ovarian cancers but other common ge...

Evaluation and treatment of BRCA-positive patients.

Solomon(J S),Brunicardi(C F),Friedman(J D) Plast Reconstr Surg 2000-03-29

...BRCA1 and BRCA2 has now made it possible to identify individuals who are at a very high risk for the future development ...

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