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TP53 BRCA1 CRISPR single-cell cancer

Maor(S B),Abramovitch(S),Erdos(M R),Brody(... Mol Genet Metab 2000-05-19

...BRCA1 expression vector, suppressed promoter activity in a dose-dependent manner. Functional interactions between BRCA1 ...

Schorge(J O),Muto(M G),Lee(S J),Huang(L W)... Cancer Res 2000-04-11

...BRCA1. In this study, we tested the hypothesis that BRCA1-related PSCP has a unique molecular pathogenesis. DNA was extr...

Sinclair(C S),Berry(R),Schaid(D),Thibodeau... Cancer Res 2000-04-11

...BRCA1 or BRCA2 truncating mutations were detected. Thus, BRCA1 and BRCA2 appear to have a limited role in familial prost...

Whittemore(A S) Cancer Epidemiol Biomarkers... 2000-05-12

...BRCA1 and BRCA2 mutation carriers, some 30% of these women are estimated to reach age 70 years without developing either...

Blesa(J R),García(J A),Ochoa(E) Hum Mutat 2000-04-28

...BRCA1 gene have been analyzed. To identify BRCA1 mutations, PTT and CSGE methods were used followed by direct sequencing...

Annab(L A),Terry(L),Cable(P L),Brady(J),St... Gynecol Oncol 2000-05-25

...BRCA1 gene. Despite being heterozygous for wild-type BRCA1, the 220-kDa full-size BRCA1 protein was abundantly expressed...

Lakhani(S R),Gusterson(B A),Jacquemier(J),... Clin Cancer Res 2000-06-01

...BRCA1/2 families). We have now characterized the pathology of 82 breast cancers from non-BRCA1/2 families. Breast cancer...

Schlegel(B P),Green(V J),Ladias(J A),Parvi... Proc Natl Acad Sci U S A 2000-04-24

...BRCA1. Excess purified Pol II subunits hRPB2 or hRPB10alpha blocked BRCA1- and VP16-dependent transcriptional activation...

Lee(J S),Collins(K M),Brown(A L),Lee(C H),... Nature 2000-04-07

...BRCA1 function after DNA damage by phosphorylating serine 988 of BRCA1. We show that hCds1 and BRCA1 interact and co-loc...

Malone(K E),Daling(J R),Neal(C),Suter(N M)... Cancer 2000-04-27

There is a clear and growing need for data regarding BRCA1 and BRCA2 mutation frequencies among breast carcinoma cases n...

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