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DNA damage-induced cell cycle checkpoints and DNA strand break repair in deve...

Dasika(G K),Lin(S C),Zhao(S),Sung(P),Tomki... Oncogene 2000-01-20

...BRCA1 and BRCA2 are involved in DNA double-strand break repair (DSBR) and DNA damage-induced checkpoint activation. Many...

BRCA1 deficient embryonic stem cells display a decreased homologous recombina...

Snouwaert(J N),Gowen(L C),Latour(A M),Mohn... Oncogene 2000-01-20

...BRCA1 expression is re-established at 5-10% of normal levels by introduction of a Brca1 transgene into BRCA1 deficient E...

Mendelian diseases among Roman Jews: implications for the origins of disease ...

Oddoux(C),Guillen-Navarro(E),Ditivoli(C),D... J Clin Endocrinol Metab 2000-01-07

...BRCA1, BRCA2, Canavan disease, Fanconi anemia complementation group C, or Tay-Sachs disease. Two unrelated individuals w...

Role of Gadd45 in apoptosis.

Sheikh(M S),Hollander(M C),Fornance(A J) Biochem Pharmacol 2000-01-06

...Brca1-induced apoptosis via activation of c-Jun N-terminal kinase (JNK) and/or p38 mitogen-activated protein kinase (MAP...

MALDI-TOF based mutation detection using tagged in vitro synthesized peptides...

Garvin(A M),Parker(K C),Haff(L) Nat Biotechnol 2000-02-29

...BRCA1 were readily identified using this method. The process can be multiplexed and is amenable to automation, providing...

Screening for BRCA2 mutations in 81 Dutch breast-ovarian cancer families.

Peelen(T),van Vliet(M),Bosch(A),Bignell(G)... Br J Cancer 2000-01-31

...BRCA1 revealed that in our study-population of 81 families, 15 families were segregating either the exon 13 or exon 22 d...

Dual immunofluorescence labeling with cell-specific markers localizes BRCA1 i...

Daniel(D C) Cell Tissue Res 2000-02-09

...BRCA1 was used for colabeling with each of these markers. Epifluorescence microscopy revealed BRCA1 immunoreactivity in ...

BRCA1 mutation testing for Japanese patients with ovarian cancer in breast ca...

Yamashita(Y),Sagawa(T),Fujimoto(T),Sugawar... Breast Cancer Res Treat 2000-02-10

...BRCA1. These characteristics may assist physicians in selecting BRCA1 mutation testing for ovarian cancer patients. The ...

Carcinosarcoma of the ovary in a patient with a germline BRCA2 mutation: evid...

Sonoda(Y),Saigo(P E),Federici(M G),Boyd(J) Gynecol Oncol 2000-02-17

...BRCA1 or BRCA2. While the occurrence of breast carcinoma and epithelial ovarian carcinoma in association with BRCA mutat...

[Molecular biology of ovarian cancer].

Tanaka(K) Gan To Kagaku Ryoho 2000-01-27

...BRCA1 is thought to be the most likely candidate for having a causal relation with the familial ovarian cancer syndrome.

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