Currently many centers offer testing for three specific mutations, 185delAG, 5382insC, and 6174delT, in the BRCA1 and BR...
...BRCA1 locus and loss of BRCA1 protein in tumors. To address whether BRCA1 may be inactivated by pathways other than muta...
The intent of this study was to evaluate the effect that an awareness of being a BRCA1 or BRCA2 mutation carrier has on ...
...BRCA1 and BRCA2. The first linkage and mutational studies suggested that mutations in these two genes would account for ...
...BRCA1 gene (exon5) was detected. The patient has been well since the operation (10 months). These findings may provide u...
...BRCA1 and BRCA2 it has been suggested that genetic screening may be of benefit for women at high familial risk. To be ab...
We have developed a 2-stage protocol for BRCA1 and BRCA2 mutation screening from blood spot paper. Stage 1 screening was...
...BRCA1 gene carriers would, therefore, be of great value. In this context, it was recently established that BRCA1-associa...
...BRCA1. In this study, we tested the hypothesis that BRCA1-related PSCP has a unique molecular pathogenesis. DNA was extr...
...BRCA1 or BRCA2 truncating mutations were detected. Thus, BRCA1 and BRCA2 appear to have a limited role in familial prost...
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