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TP53 BRCA1 CRISPR single-cell cancer

Somasundaram(K),MacLachlan(T K),Burns(T F)... Oncogene 2000-01-04

...BRCA1 can activate p53-dependent gene expression. We show here that BRCA1 increases p53 protein levels through a post-tr...

Lodder(L N),Frets(P G),Trijsburg(R W),Meij... J Med Genet 2000-01-07

...BRCA1 and BRCA2 genes in 1994-1995. Healthy female mutation carriers have a high lifetime risk for breast cancer (56-87%...

Chang-Claude(J),Becher(H),Caligo(M),Eccles... Dis Markers 2000-01-20

...BRCA1 and in 176 families for BRCA2 mutations, using different methods including SSCP, CSGE, DGGE, FAMA and PTT analysis...

Claes(K),Machackova(E),De Vos(M),Poppe(B),... Dis Markers 2000-01-20

...BRCA1 and 3 mutations in BRCA2). In 5 apparently unrelated families the same splice site mutation was identified (BRCA1 ...

Borg(A),Dørum(A),Heimdal(K),Maehle(L),Hovi... Dis Markers 2000-01-20

...BRCA1 gene was investigated for germline mutations. The entire coding region of BRCA1 was analysed using a protein trunc...

Frank(T S),Deffenbaugh(A M),Hulick(M),Gump... Dis Markers 2000-01-20

To correlate mutations in BRCA1 and BRCA2 with family history of breast cancer in a first-degree relative for women diag...

Reichelt(J G),Dahl(A A),Heimdal(K),Møller(... Dis Markers 2000-01-20

...BRCA1 mutations were offered genetic testing. 180/232 (78%) chose to be tested, 14/232 (6%) have not yet decided and 38/...

Heimdal(K),Maehle(L),Møller(P) Dis Markers 2000-01-20

...BRCA1, will increase the cost to Euro 832. Costs related more to genetic counseling and clinical follow-up than to labor...

De Vos(M),Poppe(B),Delvaux(I),Mortier(G),C... Dis Markers 2000-01-20

...BRCA1 and BRCA2 gene has been initiated, is presented. Genetic testing for breast-ovarian cancer susceptibility is offer...

Foray(N),Randrianarison(V),Marot(D),Perric... Oncogene 2000-01-06

...BRCA1 and BRCA2 genotypes after exposure to gamma-rays. A lack of functional BRCA1 and BRCA2 led to defective repair of ...

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