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The Drosophila mus101 gene, which links DNA repair, replication and condensat...

Yamamoto(R R),Axton(J M),Yamamoto(Y),Saund... Genetics 2000-11-30

...BRCA1 C terminus) domain superfamily of proteins implicated in DNA repair and cell cycle checkpoint control. Mus101, whi...

Ataxia telangiectasia-related protein is involved in the phosphorylation of B...

Chen(J) Cancer Res 2000-10-13

...BRCA1 following gamma radiation and hydroxyurea treatment. We have shown that ATR can phosphorylate several BRCA1 fragme...

Increase of androgen-induced cell death and androgen receptor transactivation...

Yeh(S),Hu(Y C),Rahman(M),Lin(H K),Hsu(C L)... Proc Natl Acad Sci U S A 2000-11-09

...BRCA1) may play important roles in breast and prostate cancers, the detailed mechanism linking the functions of BRCA1 to...

Estrogens, BRCA1, and breast cancer.

Hilakivi-Clarke(L) Cancer Res 2000-10-13

...BRCA1, and BRCA1 in turn may suppress the activity of the estrogen receptor. This review will discuss the possibility th...

Direct genomic multiplex PCR for BRCA1 and application to mutation detection ...

Barker(D F) Hum Mutat 2000-10-27

...BRCA1 coding regions and the BRCA1-specific segments from the duplicated promoter region. SSCP/HDX gel analysis of the m...

Oligonucleotide microarray based detection of repetitive sequence changes.

Hacia(J G),Edgemon(K),Fang(N),Mayer(R A),S... Hum Mutat 2000-10-27

...BRCA1 sequence tracts was prepared and evaluated. These mutations included single nucleotide insertions and deletions in...

Allelic imbalance of BRCA1 transcript in the IVS20 12-bp insertion carrier.

Kozlowski(P),Sobczak(K),Jasinska(A),Krzyzo... Hum Mutat 2000-10-27

One of the unclassified variants of the BRCA1 gene which has drawn considerable attention in recent years is the 12-bp i...

CYP17 promoter polymorphism and breast cancer in Australian women under age f...

Spurdle(A B),Hopper(J L),Dite(G S),Chen(X)... J Natl Cancer Inst 2000-11-09

...BRCA1 or BRCA2, gave a relative hazard in women with the CC genotype of 3.48 (95% CI = 1.13-10.74; P: =.04), which is eq...

[Generic screening for breast cancer].

Ponti(A),Giordano(L) Epidemiol Prev 2000-04-26

...BRCA1 and BRCA2 it has been suggested that genetic screening may be of benefit for women at high familial risk. To be ab...

An unaffected individual from a breast/ovarian cancer family with germline mu...

Moslehi(R),Russo(D),Phelan(C),Jack(E),Antm... Clin Genet 2000-04-28

Currently many centers offer testing for three specific mutations, 185delAG, 5382insC, and 6174delT, in the BRCA1 and BR...

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