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The androgen receptor exon 1 trinucleotide repeat does not act as a modifier ...

Given(H F),Radbourne(R),Oag(H),Merritt(S),... Eur J Cancer 2000-05-04

...BRCA1-associated breast cancers. We have analysed this repeat in a set of 178 breast cancer cases who have been selected...

An efficient, robust, and unified method for mapping complex traits (II): mul...

Zhao(L P),Quiaoit(F),Aragaki(C),Hsu(L) Am J Med Genet 1999-01-15

...BRCA1 and has also shown that the multipoint linkage analysis has an improved power. In addition, we have applied this m...

A phase I trial of retroviral BRCA1sv gene therapy in ovarian cancer.

Tait(D L),Obermiller(P S),Redlin-Frazier(S... Clin Cancer Res 1999-02-25

...BRCA1sv (a normal splice variant of BRCA1) into ovarian cancer cells produces growth inhibition in vitro and tumor suppr...

Germ-line BRCA1 mutation is an adverse prognostic factor in Ashkenazi Jewish ...

Foulkes(W D),Wong(N),Brunet(J S),Bégin(L R... Clin Cancer Res 1999-03-03

...BRCA1 mutation carriers compared with noncarriers. Two recurrent BRCA1 mutations (185delAG and 5382insC) are common ( ap...

Germline BRCA1 mutations and loss of the wild-type allele in tumors from fami...

Merajver(S D),Frank(T S),Xu(J),Pham(T M),C... Clin Cancer Res 1999-02-08

...BRCA1 have been determined; analyses of tumors with LOH at BRCA1 have revealed that only the disease-related allele of B...

Sequence analysis of the rat Brca1 homolog and its promoter region.

Bennett(L M),Brownlee(H A),Hagavik(S),Wise... Mamm Genome 1999-03-01

Since the identification of the human breast and ovarian cancer gene, BRCA1, a large spectrum of germline mutations has ...

Activation of transcription in vitro by the BRCA1 carboxyl-terminal domain.

Haile(D T),Parvin(J D) J Biol Chem 1999-02-16

...BRCA1 fusion protein were stronger when in the presence of certain coactivators. The transcriptional activation by BRCA1...

Current methods to prevent the development of breast cancer.

Cristofanilli(M),Hortobagyi(G N) In Vivo 1999-04-19

...BRCA1 and BRCA2 breast cancer susceptibility genes have provided the opportunity for identification of high risk women. ...

Inherited breast cancer: an emerging picture.

Welcsh(P L),Schubert(E L),King(M C) Clin Genet 1999-04-13

...BRCA1 and BRCA2 related? BRCA1 and BRCA2 may maintain the integrity of the genome by regulating expression of genes dire...

Somatic genetic alterations in BRCA2-associated and sporadic male breast cancer.

Tirkkonen(M),Kainu(T),Loman(N),Jóhannsson(... Genes Chromosomes Cancer 1999-06-11

...BRCA1 or BRCA2 mutation follows specific genetic pathways, distinct from each other and from sporadic breast cancer. In ...

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