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Germline PTEN mutations in Cowden syndrome-like families.

Marsh(D J),Dahia(P L),Caron(S),Kum(J B),Fr... J Med Genet 1999-02-04

...BRCA1, BRCA2, and p53, have been associated with familial breast or breast/ovarian cancer families. Given the involvemen...

Awareness and attitudes concerning BRCA gene testing.

Mogilner(A),Otten(M),Cunningham(J D),Browe... Ann Surg Oncol 1999-02-04

The availability of a commercial test for the breast cancer susceptibility genes, BRCA1 and BRCA2, has generated interes...

A targeted disruption of the murine Brca1 gene causes gamma-irradiation hyper...

Shen(S X),Weaver(Z),Xu(X),Li(C),Weinstein(... Oncogene 1999-01-26

...Brca1-/- fibroblasts are not viable, nor are Brca1-/-:p53-/- fibroblasts. However, proliferative foci arise from Brca1-/...

Down-regulation of BRCA1 in human sporadic breast cancer; analysis of DNA met...

Magdinier(F),Ribieras(S),Lenoir(G M),Frapp... Oncogene 1999-01-26

...BRCA1 have not been detected and in vitro experiments have indicated that BRCA1 negatively regulates cellular proliferat...

An efficient, robust, and unified method for mapping complex traits (II): mul...

Zhao(L P),Quiaoit(F),Aragaki(C),Hsu(L) Am J Med Genet 1999-01-15

...BRCA1 and has also shown that the multipoint linkage analysis has an improved power. In addition, we have applied this m...

Mutations in the BRCA1 gene: implications of inter-population differences for...

Chakraborty(R),Sankaranarayanan(K) Genet Res 1999-03-29

...BRCA1 mutant gene frequencies; the estimates of the strength of predisposition and radiosensitivity differentials used a...

Multiple target sites of allelic imbalance on chromosome 17 in Barrett's oeso...

Dunn(J),Garde(J),Dolan(K),Gosney(J R),Sutt... Oncogene 1999-02-23

...BRCA1 (17q21.1), and a putative TSG (17p13.3). The tumours all displayed relatively small regions of LOH (1-10 cM), and ...

Survival after breast cancer in Ashkenazi Jewish BRCA1 and BRCA2 mutation car...

Lee(J S),Wacholder(S),Struewing(J P),McAda... J Natl Cancer Inst 1999-03-04

...BRCA1 and/or BRCA2 mutations and noncarriers.,Carriers of BRCA1 and BRCA2 mutations appeared to have neither better nor ...

Current policies for surveillance and management in women at risk of breast a...

Vasen(H F),Haites(N E),Evans(D G),Steel(C ... Eur J Cancer 1999-02-25

The recent isolation of breast cancer predisposing genes (BRCA1 and BRCA2) allows the identification of carriers within ...

The genetic basis of breast cancer and its clinical implications.

Bennett(I C),Gattas(M),Teh(B T) Aust N Z J Surg 1999-03-02

...BRCA1, BRCA2, ATM gene, PTEN and p53. Several other less frequently occurring predisposition genes such as the androgen ...

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