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Survival in familial, BRCA1-associated, and BRCA2-associated epithelial ovari...

Pharoah(P D),Easton(D F),Stockton(D L),Gay... Cancer Res 1999-03-04

...BRCA1- and BRCA2-associated hereditary ovarian cancer, hereditary ovarian cancer with no identified BRCA1/2 mutation, an...

Mapping the functional domains of BRCA1. Interaction of the ring finger domai...

Meza(J E),Brzovic(P S),King(M C),Klevit(R ... J Biol Chem 1999-03-18

...BRCA1) and BRCA1-associated RING domain 1 (BARD1) are multidomain proteins that interact in vivo via their N-terminal RI...

Structure and expression of variant BRCA2a lacking the transactivation domain...

Zou(J P),Hirose(Y),Siddique(H),Rao(V N),Re... Oncol Rep 1999-04-01

BRCA1 and BRCA2 are tumor suppressor genes shown to be involved in 90% of familial breast cancers and also known to be i...

Loss of heterozygosity at 8p, 9p and 17q in laryngeal cytological specimens.

Rizos(E),Sourvinos(G),Spandidos(D A) Oral Oncol 1999-02-17

...BRCA1 with an important role in the multistage carcinogenesis of the larynx. In order to investigate the implication of ...

[Loss of heterozygosity and microsatellite instability in the region includin...

Cui(J),Shen(F),Jiang(F),Wang(Y),Bian(J),Sh... Zhonghua Yi Xue Yi Chuan Xu... 1999-01-28

To shed light on the relationship between BRCA1 gene and breast cancer in Chinese Han women.,Four microsatellites DNA (D...

Predicted anti-oestrogen resistance in BRCA-associated familial breast cancer...

Osin(P),Gusterson(B A),Philp(E),Waller(J),... Eur J Cancer 1999-01-25

...BRCA1 and BRCA2. This study was carried out to assess the likely hormone dependence of this group of tumours in comparis...

Loss of heterozygosity of BRCA1, TP53 and TCRD markers analysed in sporadic e...

Niederacher(D),An(H X),Camrath(S),Dominik(... Eur J Cancer 1999-01-25

...BRCA1 was detected in 18.1%, of TP53 in 26.9%, and of TCRD in 26.3% of informative cases. LOH of BRCA1 correlated with m...

Somatic genetic alterations in BRCA2-associated and sporadic male breast cancer.

Tirkkonen(M),Kainu(T),Loman(N),Jóhannsson(... Genes Chromosomes Cancer 1999-06-11

...BRCA1 or BRCA2 mutation follows specific genetic pathways, distinct from each other and from sporadic breast cancer. In ...

Sequence analysis of the rat Brca1 homolog and its promoter region.

Bennett(L M),Brownlee(H A),Hagavik(S),Wise... Mamm Genome 1999-03-01

Since the identification of the human breast and ovarian cancer gene, BRCA1, a large spectrum of germline mutations has ...

Reliable and sensitive detection of premature termination mutations using a p...

Bateman(J F),Freddi(S),Lamandé(S R),Byers(... Hum Mutat 1999-06-10

...BRCA1). The greatly increased sensitivity and reliability of this RT-PCR/PTT protocol has broad applicability to the man...

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