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Loss of heterozygosity at 8p, 9p and 17q in laryngeal cytological specimens.

Rizos(E),Sourvinos(G),Spandidos(D A) Oral Oncol 1999-02-17

...BRCA1 with an important role in the multistage carcinogenesis of the larynx. In order to investigate the implication of ...

The genetics of breast cancer susceptibility.

Rahman(N),Stratton(M R) Annu Rev Genet 1999-03-03

...BRCA1 and BRCA2, the basic patterns of cancer risk associated with mutations in these genes have been defined. In additi...

Prevention of breast cancer: focus on chemoprevention.

Costa(A),Bonanni(B),Manetti(L),Guerrieri G... Recent Results Cancer Res 1999-03-12

...BRCA1 mutation carriers). Secondary chemoprevention may involve subjects with premalignant or early malignant lesions, e...

Update on breast cancer susceptibility genes.

Weber(B L) Recent Results Cancer Res 1999-03-12

BRCA1 and BRCA2 have now been isolated and a large number of families characterized for the presence of mutations in the...

A population-based study of BRCA1 and BRCA2 mutations in Jewish women with ep...

Lu(K H),Cramer(D W),Muto(M G),Li(E Y),Nilo... Obstet Gynecol 1999-02-17

To determine the frequency of BRCA1 mutations 185delAG and 5382insC and BRCA2 mutation 6174delT in Jewish women with ova...

Screening for genetic risk of breast cancer.

Rosenthal(T C),Puck(S M) Am Fam Physician 1999-02-04

...BRCA1 mutation also have a substantially increased risk of ovarian cancer. BRCA1 and 2 mutations are associated with ear...

Identification of the 185delAG BRCA1 mutation in a Spanish Gypsy population.

Díez(O),Doménech(M),Alonso(M C),Brunet(J),... Hum Genet 1999-02-09

...BRCA1 deletion occurs with a high frequency in Ashkenazi Jews. We detected this mutation in two Spanish Gypsy women (the...

Predicted anti-oestrogen resistance in BRCA-associated familial breast cancer...

Osin(P),Gusterson(B A),Philp(E),Waller(J),... Eur J Cancer 1999-01-25

...BRCA1 and BRCA2. This study was carried out to assess the likely hormone dependence of this group of tumours in comparis...

Loss of heterozygosity of BRCA1, TP53 and TCRD markers analysed in sporadic e...

Niederacher(D),An(H X),Camrath(S),Dominik(... Eur J Cancer 1999-01-25

...BRCA1 was detected in 18.1%, of TP53 in 26.9%, and of TCRD in 26.3% of informative cases. LOH of BRCA1 correlated with m...

[Natural history of ovarian adenocarcinomas: from epidemiology to experimenta...

Hamilton(T C),Penault-Llorca(F),Dauplat(J) Contracept Fertil Sex 1999-02-26

...BRCA1 mutation provides ovaries that can be compared to a control group. Epithelial or stromal changes are observed in t...

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