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BRCA1 gene mutation and loss of heterozygosity on chromosome 17q21 in primary...

Uchida(T),Wang(C),Sato(T),Gao(J),Takashima... Int J Cancer 1999-02-23

...BRCA1 gene, and a sister of this patient died of ovarian cancer. It appears that the BRCA1 gene is not frequently involv...

Localization of human BRCA1 and its loss in high-grade, non-inherited breast ...

Wilson(C A),Ramos(L),Villaseñor(M R),Ander... Nat Genet 1999-02-25

...BRCA1 in non-familial cancers is unclear. BRCA1 mutations are rare in sporadic cancers, but loss of BRCA1 resulting from...

Current policies for surveillance and management in women at risk of breast a...

Vasen(H F),Haites(N E),Evans(D G),Steel(C ... Eur J Cancer 1999-02-25

The recent isolation of breast cancer predisposing genes (BRCA1 and BRCA2) allows the identification of carriers within ...

Multiple target sites of allelic imbalance on chromosome 17 in Barrett's oeso...

Dunn(J),Garde(J),Dolan(K),Gosney(J R),Sutt... Oncogene 1999-02-23

...BRCA1 (17q21.1), and a putative TSG (17p13.3). The tumours all displayed relatively small regions of LOH (1-10 cM), and ...

Mapping the functional domains of BRCA1. Interaction of the ring finger domai...

Meza(J E),Brzovic(P S),King(M C),Klevit(R ... J Biol Chem 1999-03-18

...BRCA1) and BRCA1-associated RING domain 1 (BARD1) are multidomain proteins that interact in vivo via their N-terminal RI...

The genetic basis of breast cancer and its clinical implications.

Bennett(I C),Gattas(M),Teh(B T) Aust N Z J Surg 1999-03-02

...BRCA1, BRCA2, ATM gene, PTEN and p53. Several other less frequently occurring predisposition genes such as the androgen ...

Survival in familial, BRCA1-associated, and BRCA2-associated epithelial ovari...

Pharoah(P D),Easton(D F),Stockton(D L),Gay... Cancer Res 1999-03-04

...BRCA1- and BRCA2-associated hereditary ovarian cancer, hereditary ovarian cancer with no identified BRCA1/2 mutation, an...

Mutations in the BRCA1 gene: implications of inter-population differences for...

Chakraborty(R),Sankaranarayanan(K) Genet Res 1999-03-29

...BRCA1 mutant gene frequencies; the estimates of the strength of predisposition and radiosensitivity differentials used a...

Survival after breast cancer in Ashkenazi Jewish BRCA1 and BRCA2 mutation car...

Lee(J S),Wacholder(S),Struewing(J P),McAda... J Natl Cancer Inst 1999-03-04

...BRCA1 and/or BRCA2 mutations and noncarriers.,Carriers of BRCA1 and BRCA2 mutations appeared to have neither better nor ...

Structure and expression of variant BRCA2a lacking the transactivation domain...

Zou(J P),Hirose(Y),Siddique(H),Rao(V N),Re... Oncol Rep 1999-04-01

BRCA1 and BRCA2 are tumor suppressor genes shown to be involved in 90% of familial breast cancers and also known to be i...

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