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[Genetic predisposition to breast cancer: a review in April 1998].

Stoppa-Lyonnet(D) Contracept Fertil Sex 1999-11-02

...BRCA1 and BRCA2 genes allows to understand in an increasing number of cases the origin of a breast/ovarian cancer family...

BRCA1 mutation analysis in 83 Spanish breast and breast/ovarian cancer families.

Díez(O),Cortés(J),Domènech(M),Brunet(J),De... Int J Cancer 1999-11-18

A group of 83 Spanish BC/OC families were analysed for BRCA1 germ-line mutations. Analysis of the entire coding sequence...

Detection of loss of heterozygosity at RAD51, RAD52, RAD54 and BRCA1 and BRCA...

Gonzalez(R),Silva(J M),Dominguez(G),Garcia... Br J Cancer 1999-10-14

...BRCA1, BRCA2 and possibly other genes implicated in the repair of double-stranded DNA and in DNA recombination. We inves...

Methylation-sensitive, single-strand conformation analysis (MS-SSCA): A rapid...

Bianco(T),Hussey(D),Dobrovic(A) Hum Mutat 1999-11-05

...BRCA1 promoter CpG island in breast cancer samples. About 20% of sporadic breast cancers are hypermethylated at the BRCA...

A highly sensitive, fast, and economical technique for mutation analysis in h...

Arnold(N),Gross(E),Schwarz-Boeger(U),Pfist... Hum Mutat 1999-11-05

...BRCA1 mutations were tested. Of 1,518 amplicons analyzed by DHPLC, corresponding to 33 fragments spanning the entire BRC...

Association of BRCA1 with the hRad50-hMre11-p95 complex and the DNA damage re...

Zhong(Q),Chen(C F),Li(S),Chen(Y),Wang(C C)... Science 1999-08-16

...BRCA1 but was restored by transfection of wild-type BRCA1. Ectopic expression of wild-type, but not mutated, BRCA1 in th...

BRCA1 mutations in familial ovarian cancer.

Lallas(T A),Buekers(T E),Buller(R E) Mol Genet Metab 1999-09-22

BRCA1 mutation research in ovarian and breast cancer 17q21-linked families has yielded a large number of germline sequen...

Molecular genetics of breast cancer progression.

Ingvarsson(S) Semin Cancer Biol 1999-10-07

...BRCA1 or BRCA2 gene have an increase of additional genetic defects compared with sporadic breast tumors. This higher fre...

BRCA1 and BRCA2 genes: role in hereditary breast and ovarian cancer in Italy.

Santarosa(M),Dolcetti(R),Magri(M D),Crivel... Int J Cancer 1999-09-10

...BRCA1 gene. The coding region and splice boundaries of BRCA2 and BRCA1 genes were assessed by the protein-truncation tes...

Histological type and syncytial growth pattern affect E-cadherin expression i...

Jacquemier(J),Eisinger(F),Noguès(C),Sun(Z ... Int J Cancer 1999-09-10

...BRCA1-associated breast cancers (BRCA1-BCs), we investigated E-cadherin expression by immuno-histochemistry in a combine...

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